Somatosensory Stimulation for Unilateral Neglect After Stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This feasibility study explores whether a hands-on physical therapy technique called Mobilization and Tactile Stimulation (MTS) can improve neglect symptoms and upper limb function in adults with stroke. It uses a mixed-methods, single-subject design to observe changes before, during, and after MTS, complemented by qualitative feedback. Participants must have unilateral neglect, be at least 20 weeks post-stroke, and have a caregiver available to assist with home-based therapy over about three months. The study will document feasibility, acceptability, and potential signals of benefit using existing clinical observations and planned outcome measures. The approach builds on routine therapy for the affected arm, focusing on somatosensory input through touch, proprioception, and manual techniques.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult (≥18 years of age) who is an Adult stroke survivors (≥18 years of age) with a clinical diagnosis of UN, in the subacute-chronic phase of stroke (≥20 weeks post stroke)
* Ability to consent to participate in the study, assessed by their understanding of the study when it is explained to them.
* Sufficient cognitive and physical ability to allow inclusion in this study, assessed by the ability to follow a simple one-stage command with the non-paretic limb.
* Able and willing to receive and engage with regular therapy (MTS) (e.g. at home).

Exclusion Criteria:

* Stroke survivor with major communication problems (e.g receptive aphasia) that affect their understanding of the treatment, their ability to follow instruction, or ability to consent to participate.
* Participants who do not speak/understand English and who do not have access to an interpreter.

Where it's running

• Midlands Partnership University NHS Foundation Trust
  Newcastle-under-Lyme, United Kingdom Recruiting

Study contacts

• Study coordinator: Ali Aries, PhD
• Email: a.m.aries@keele.ac.uk
• Phone: 07713278910

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.