Slow-coagulation trans-scleral cyclophotocoagulation versus trabeculectomy with mitomycin C for uncontrolled open-angle glaucoma after cataract surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional comparison enrolls pseudophakic patients with open-angle glaucoma whose intraocular pressure remains high despite medical therapy. Participants receive either slow-coagulation trans-scleral cyclophotocoagulation (SC-TSCPC) or trabeculectomy with mitomycin C and are followed for post-procedure intraocular pressure, need for glaucoma medications, visual field status, and complications. The trial focuses on patients with moderate visual field loss and defects outside the central 5 degrees. Outcomes will inform relative effectiveness and safety profiles of a laser cyclodestructive approach versus a traditional filtration surgery in this patient group.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1\. Patients above 40 years old.

  2\. POAG who underwent previous uncomplicated cataract surgery with intraocular lens implantation.

  3\. Pseudophakic patients with medically uncontrolled glaucoma in spite of the use of two anti-glaucoma medications or intolerance to medical therapy.

  4\. Visual field defects in both the superior and inferior hemi-fields outside the central 5 degrees of fixation.

  5\. Mean deviation on perimetry ranges between -6 dB and -12 dB

Exclusion Criteria:

* 1\. Patients with history of previous glaucoma surgery. 2. Patients who have used topical steroids within the last three months. 3. Patients with significant media opacity, such as corneal opacity, that obstructs fundoscopic examination.

  4\. Patients with ocular diseases as uveitis. 5. Patients with severe ocular surface disorders as ocular cicatricial pemphigoid.

  6\. Aphakic patients. 7. Ocular interventions apart from YAG posterior capsulotomy.

Where it's running

• Minia University Hospital
  Minya, Egypt Recruiting

Study contacts

• Study coordinator: Hazem M Abdelaziz, Master
• Email: hazem.m.abdelaziz@mu.edu.eg
• Phone: 01010045499

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.