Evaluating the safety and effectiveness of iDose TR with cataract surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial assesses the safety and intraocular pressure (IOP) lowering effects of the iDose TR (travoprost intracameral implant) when administered during cataract surgery compared to cataract surgery alone. It is a Phase 4 randomized, double-masked, parallel group trial involving patients diagnosed with open-angle glaucoma or ocular hypertension. The study aims to determine if the combination of iDose TR and cataract surgery provides better outcomes than cataract surgery by itself.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Cataract diagnosis: clinically significant age-related cataract eligible for phacoemulsification in the study eye.
* OAG or OHT diagnosis: either OAG (i.e. primary, pseudoexfoliation, or pigmentary glaucoma) or OHT in the study eye (i.e., eye to undergo cataract surgery)

Exclusion Criteria:

* Active corneal inflammation or edema.
* Retinal disorders not associated with glaucoma.

Where it's running

• Glaukos Investigator Site
  Kenosha, Wisconsin, United States Recruiting

Study contacts

• Study coordinator: Study Manager
• Email: ClinicalResearch@glaukos.com
• Phone: 949-739-8749

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Pregabalin eye drops vs timolol eye drops for open-angle glaucoma or ocular hypertension

  A doctor-led study tests whether pregabalin eye drops (TB0001) work as well as timolol eye drops to lower eye pressure in adults with glaucoma or high eye pressure.

  Recruiting at 3 sites Phase 2 Tavo Biotherapeutics · Glendale, California and 2 other locations · NCT07913074

• iDose TR implant administration in an office-based eye clinic

  This study tests a travoprost implant (iDose TR) given inside the eye to people with open-angle glaucoma or high eye pressure in an office setting to see if it is safe.

  Recruiting Glaukos Corporation · Austin, Texas · NCT07816692

• REGN22530 for Adults With Primary Open Angle Glaucoma or Ocular Hypertension

  This study tests REGN22530 in adults with POAG or ocular hypertension to see if it can lower eye pressure and what kind of side effects it may have.

  Recruiting Phase 1/2 Regeneron Pharmaceuticals · Deerfield Beach, Florida · NCT07675824

• Comparison of Unity and Centurion phacoemulsification systems for bilateral cataract surgery

  This test compares the Unity and Centurion phacoemulsification systems to see which uses less ultrasound time and cumulative dispersed energy in adults having sequential bilateral cataract surgery for nuclear sclerosis.

  Recruiting Advanced Vision Care · Los Angeles, California · NCT07468877

• Direct (non-contact) laser versus standard selective laser for treating glaucoma

  This test compares a newer non-contact laser (DSLT) with the standard SLT to see if it lowers eye pressure just as well in adults with open-angle glaucoma or ocular hypertension.

  Recruiting Medical University of South Carolina · Charleston, South Carolina · NCT07408154

• Slow-coagulation trans-scleral cyclophotocoagulation versus trabeculectomy with mitomycin C for uncontrolled open-angle glaucoma after cataract surgery

  This trial will test whether slow-coagulation trans-scleral cyclophotocoagulation or trabeculectomy with mitomycin C better lowers eye pressure in people over 40 with pseudophakic open-angle glaucoma not controlled by medications.

  Recruiting Minia University · Minya · NCT07152132

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.