Clinical trial Recruiting at 1 site Observational Ages 18 to 65

Sleep quality and how it affects thinking, activity, and reaction time in people with multiple sclerosis

Official title: Effects of Sleep Quality on Cognitive Flexibility, Physical Activity, Body Awareness, and Reaction Time in Multiple Sclerosis

Run by Ankara University · NCT07536503 · Data updated 2026-11-12

This study will see if having good or poor sleep changes thinking flexibility, activity levels, body awareness, and reaction time in adults with multiple sclerosis.

Quick facts

Study typeObservational
Ages18 Years to 65 Years
SexAll
Enrollment80 (estimated)
SponsorAnkara University
Academic / other
Locations1 site (Ankara, Ankara)
StatusRecruiting
StartedMay 1, 2026
Main results expectedJuly 1, 2026
Study endsAugust 1, 2026
Registry record updatedJune 2, 2026
Trial IDNCT07536503 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18-65 with a confirmed MS diagnosis, MoCA ≥24, and EDSS 0–6.5 who are not experiencing a relapse in the past 3 months.

Probably not a fit

Individuals with comorbid conditions or impairment that prohibits safe wear of activity trackers or completing tests may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study in adults with multiple sclerosis. Researchers will categorize participants by sleep quality and compare cognitive flexibility, physical activity, body awareness, and reaction time between groups. Participants will complete standardized sleep and cognitive tests, wear a device to track activity for 7 days, and perform computer-based reaction time tasks. The study aims to uncover associations between sleep quality and functional performance in MS. No intervention will be given; data will be analyzed to identify potential links between sleep and outcomes.

Why it matters

Potential benefit: If a link is found, interventions to improve sleep could help enhance cognitive and physical function in MS.

How similar studies have gone: Previous observational work suggests sleep quality can relate to cognitive and physical performance in neurological conditions, making this approach plausible in MS.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 18 and 65 years
* Diagnosis of Multiple Sclerosis
* Montreal Cognitive Assessment (MoCA) score ≥24
* Expanded Disability Status Scale (EDSS) score between 0 and 6.5
* No relapse within the last 3 months
* Voluntary participation with written informed consent

Exclusion Criteria:

* Presence of other neurological, psychiatric, or systemic diseases
* Severe visual, auditory, or balance impairments
* History of surgery within the last 6 months
* Use of sleep medication or central nervous system-affecting drugs
* Severe orthopedic deformity or pain

Where it's running

  • Baskent University Ankara Hospital
    Ankara, Ankara, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.