Skincare regimen for mild to moderate acne in people with sensitive skin

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an interventional study testing a multi-product skincare regimen (cleansing, toning, serum, day cream, night cream) in adults with sensitive skin who have mild to moderate acne. Participants will use the regimen for 4 weeks, with skin assessments at baseline and at week 4 to gauge safety and efficacy. The study will also gather participant satisfaction regarding the regimen. Eligible participants are healthy Malaysian adults with sensitive skin and acne, while several conditions (pregnancy, autoimmune disorders, and severe acne requiring medical therapy) exclude enrollment. No collaborative institutions are listed beyond USMARI Research & Innovation Centre in Petaling Jaya.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy Malaysian women and men
* Fitzpatrick skin type II-V
* Age above 18 years old
* Individuals with sensitive skin identify through sensitive skin survey (Corazza et al., 2022) and lactic acid sting test (LAST).
* Individuals with mild to moderate acne, based on Comprehensive Acne Severity Scale (CASS)

Exclusion Criteria:

* Pregnant or breastfeeding women, or those planning pregnancy during the study period.
* Individuals with documented autoimmune diseases or other conditions that may affect immune response or skin barrier function.
* Individuals with a history of severe skin sensitivity reactions, including frequent intense erythema, swelling, or intolerable burning in response to topical products.
* Individuals with severe acne requiring medical treatment or systemic treatment such as nodulocystic acne.
* Individuals with active inflammatory or allergic dermatological conditions affecting the face, such as atopic dermatitis, eczema, or psoriasis, which may compromise skin barrier function or interfere with study assessments.
* Individuals who have undergone cosmetic or dermatological procedures such as -chemical peel, microneedling, or any procedures aimed at improving acne, within 3 months prior to the study.
* Individuals currently taking medical or hormonal treatments that may interfere with study outcomes, including anti-inflammatory agents, corticosteroids, or other medication interfering with study objectives.
* Individuals with known allergy or hypersensitivity to any ingredients found in the product.

Where it's running

• USMARI Research & Innovation Centre
  Petaling Jaya, Selangor, Malaysia Recruiting

Study contacts

• Study coordinator: Siti Nur Hanis Mamood, PhD
• Email: hanis@usmari.org.my
• Phone: +60167572670

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.