Shortness of breath in autoimmune myasthenia gravis: causes and testing

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

MYaResp is a prospective observational, cross-sectional study that examines breathlessness in adults with autoimmune myasthenia gravis. Adults who report daily-life shortness of breath will complete questionnaires and undergo clinical and physiological testing to characterize the sensation, its severity, and its functional impact. The study will compare patient-reported dyspnea with disease severity measures and objective tests to identify contributing factors and the most informative diagnostic tests. Results are intended to inform targeted management strategies and monitoring to reduce respiratory deterioration and improve quality of life.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥18
* Confirmed diagnosis of autoimmune MG
* Shortness of breath in daily life: score 1 or 2 on the respiration item on the MG- activities of daily living score
* Signed consent form
* Affiliated to or beneficiary of a social security scheme

Exclusion Criteria:

* Known Pregnancy
* Known respiratory disorder (other than MG)
* Recent (within past 4 weeks) respiratory infection
* Current MG crisis or exacerbation (necessitating increase in MG medication \&/or hospital admission)
* No dyspnea - score 0 or 3 on the respiration item on the MG- activities of daily living score
* Severe cognitive impairment/guardianship

Where it's running

• Institute of Myology
  Paris, France Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.