Serratus Anterior Block for Pain Relief After Mastectomy

Ultrasound-Guided Erector Spinae Block Versus Serratus Anterior Block for Perioperative Analgesia In Patients Undergoing Modified Radical Mastectomy Surgery

Not applicable Interventional Zagazig University · NCT06410378

This study is testing if two new pain relief methods can help women feel better after having breast surgery and reduce the need for strong pain medications.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment75 (estimated)
Ages21 Years to 60 Years
SexFemale
SponsorZagazig University Government
Drugs / interventionsradiation
Locations1 site (Zagazig, MD)
Trial IDNCT06410378 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of the Serratus Anterior Block and Erector Spinae Plane Block as regional anesthesia techniques for managing postoperative pain in women undergoing modified radical mastectomy. The study aims to reduce opioid consumption and associated side effects by providing effective perioperative analgesia through these innovative regional blocks. Participants will be monitored for pain relief and recovery profiles to assess the safety and efficacy of these techniques compared to traditional methods.

Who should consider this trial

Good fit: Ideal candidates for this study are female patients aged 21 to 60 years who are undergoing unilateral modified radical mastectomy.

Not a fit: Patients with chronic pain conditions, anatomical abnormalities, or contraindications to regional anesthesia may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce postoperative pain and opioid-related side effects for women undergoing mastectomy.

How similar studies have performed: Other studies have shown promising results with similar regional anesthesia techniques, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Written informed consent from the patient.

  * Age: 21 - 60 years old.
  * Gender: female patients.
  * Body mass index: \< 35 kg/m2.
  * Physical status: ASA grade I-II (American society of anesthiologists).
  * Type of operation: unilateral modified radical mastectomy operation.

Exclusion Criteria:

* • Patient with known history of allergy to study drugs.

  * Chronic use of analgesics or drug dependence.
  * Patients not able to understand pain assessment test.
  * Anatomical abnormalities.
  * Neuropathic disease.
  * Pregnancy or breast feeding.
  * Other contraindication of regional anesthesia e.g. septic focus at site of injection.
  * patient with coagulopathy or on anticoagulant therapy.

Where this trial is running

Zagazig, MD

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions MastectomyPostoperative PainErector Spinae BlockSerratus anterior BlockPerioperative Analgesia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.