Sepsis Chart Implementation and 7-Day Mortality in Indonesian Hospitals

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates the impact of implementing a paper-based sepsis chart, designed to guide the One-hour Sepsis Bundle, on adherence to early sepsis management and 7-day mortality among adults with sepsis presenting to the Emergency Department. Researchers compare outcomes before and after the chart's introduction at two tertiary hospitals in Jakarta. Participants receive standard sepsis care with documentation focused on the first hour after sepsis suspicion or diagnosis. The study addresses whether a structured order set can improve timely interventions and survival in a real-world LMIC setting. The One-hour Sepsis Bundle includes rapid lactate measurement, cultures, and timely antibiotic administration, among other components.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients aged ≥18 years.
* Patients diagnosed with sepsis according to the Sepsis-3 definition, using the lactate-modified qSOFA score as a reference.
* Patients presenting to the Emergency Department.
* Patients who are subsequently admitted to one of the participating hospitals: Cipto Mangunkusumo and Fatmawati General Hospital.

Exclusion Criteria:

* Incomplete clinical or outcome data required for the study analysis.

Where it's running

• Dr Cipto Mangunkusumo General Hospital
  Jakarta Pusat, DKI Jakarta, Indonesia Recruiting
• Fatmawati General Hospital
  Jakarta Pusat, DKI Jakarta, Indonesia Not yet recruiting

Study contacts

• Study coordinator: Sharifah Shakinah, MD
• Email: sharifah.shakinah@gmail.com
• Phone: +628129670607

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.