Self-administered acupressure for alleviating depression

Self-administered Acupressure for Depression: A Randomized Controlled Trial

Not applicable Interventional The Hong Kong Polytechnic University · NCT05631184

This study tests if doing self-acupressure can help people with depression feel better compared to a group that receives mental health education.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment250 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorThe Hong Kong Polytechnic University Academic / other
Locations1 site (Hong Kong)
Trial IDNCT05631184 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of self-administered acupressure in reducing depressive symptoms among individuals diagnosed with depression. Participants will be randomly assigned to either the acupressure group or a mental health education group, with the aim of comparing the outcomes over a 12-week intervention period. The study will measure changes in depressive symptoms using the Patient Health Questionnaire and assess the feasibility and acceptability of the acupressure intervention for participants.

Who should consider this trial

Good fit: Ideal candidates are Hong Kong residents aged 18 to 65 with moderate depression, as indicated by a PHQ-9 score of 10 or above.

Not a fit: Patients with severe depression (PHQ score of 20 or above) or those with significant cognitive impairment or psychotic disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could provide a non-pharmacological option for individuals struggling with depression.

How similar studies have performed: Previous studies have shown promising results for acupressure in managing depressive symptoms, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Hong Kong residents aged 18 to 65
2. Can communicate in Cantonese and comprehend written Chinese
3. Have moderate or above-level depression as measured by the PHQ-9 with a score of 10 or above
4. Willing to give informed consent and comply with the trial protocol.

Exclusion Criteria:

1. Have the PHQ score of 20 or above (referral information to community psychological services will be provided)
2. New onset or change of antidepressant medication or dosage in the last 3 months
3. Previous or current diagnosis of schizophrenia, other psychotic disorders, or bipolar disorder as screened using the Chinese version of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders.
4. Have cognitive impairment diagnosed by the Hong Kong Montreal Cognitive Assessment with a score \< 22
5. Skin lesions or infections at the treatment sites
6. Significant suicidal risk as rated by the Hamilton Depression Rating Scale item on suicide (score ≥3)
7. Pregnant or childbearing potential but not using adequate contraception
8. With any major medical condition that causes depression based on the judgement of a psychiatrist.

Where this trial is running

Hong Kong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Depressive SymptomsDepressive DisorderDepressionAcupressureRandomized Controlled Trial
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.