See if smelling tests and guidance improve well-being for people with smell loss

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This phase 2, randomized study will enroll participants with olfactory dysfunction to receive patient-centered information and education based on smell testing results, delivered in person or remotely. Researchers will measure odor detection, intensity, identification, pleasantness, and discrimination, then assess psychological health and care-seeking at 1 month and 6 months. The study uses predefined cut-offs to classify participants as having smell dysfunction or normosmia and compares outcomes between groups over time. Data will be collected via surveys and follow-up contacts to evaluate changes in well-being and engagement with care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- Can read and understand English and have access to a reliable internet connection and a smart device or computer for the duration of the experimental sessions, unless they are part of community events in which smart devices are provided

Exclusion Criteria:

\- Known intolerance or allergy to any of the odor stimuli used

Where it's running

• Monell Chemical Senses Center
  Philadelphia, Pennsylvania, United States Recruiting

Study contacts

• Principal investigator: Valentina Parma — Monell Chemical Senses Center
• Study coordinator: Valentina Parma
• Email: vparma@monell.org
• Phone: +1 (267) 519 - 4680

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.