See if inflammation and scarring in Crohn's can be mapped from resected tissue

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will perform comprehensive ex vivo multiparametric MRI on resected Crohn’s tissue, alongside biophysical measurements and histopathology, to map inflammation and fibrosis. The goal is to validate MRI biomarkers that could be used in living patients to tailor therapy and improve flare detection. The study uses tissue from adults undergoing intestinal resection at CHRU Nancy, focusing on precise tissue characterization beyond current imaging. This is an observational effort to correlate ex vivo findings with in vivo MRI signals. No interventions are being tested in this protocol.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years.
* Diagnosis of Crohn's disease and undergoing intestinal resection surgery at CHRU Nancy.
* Patient has not objected to the reuse of personal data and biological samples for the purposes of this research.

Exclusion Criteria:

\- None

Where it's running

• CHRU Nancy
  Vandœuvre-lès-Nancy, France Recruiting

Study contacts

• Study coordinator: Guillaume DROUOT, PhD
• Email: g.drouot@chru-nancy.fr
• Phone: +33383157666

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.