Seated brain-gut yoga for functional dyspepsia and gastroparesis
Adaptation of the Yoga Skills Training for Relief of Nausea and Vomiting in Patients With Functional Dyspepsia and Gastroparesis
This program will try a seated yoga routine to see if it is practical and acceptable for adults with functional dyspepsia or gastroparesis.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 10 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Wake Forest University Health Sciences Academic / other |
| Locations | 1 site (Charlotte, North Carolina) |
| Trial ID | NCT06732453 on ClinicalTrials.gov |
What this trial studies
This pilot adapts a seated yoga intervention originally designed for gastrointestinal cancer patients for use in people with functional dyspepsia or gastroparesis. Participants will complete a field test of the seated yoga skills training at an outpatient clinic to measure feasibility, adherence, and acceptability. Eligible adults will be screened to exclude active GI comorbidities, recent regular yoga or meditative movement practice, and certain psychiatric or substance-use risks. Study findings will be used to refine the intervention and study procedures for future trials.
Who should consider this trial
Good fit: Adults aged 18 and over with physician-diagnosed functional dyspepsia or gastroparesis who can read English and have not practiced regular yoga, tai chi, or qigong in the past six months are ideal candidates.
Not a fit: Patients with active excluded GI diseases, recent GI surgery, current psychosis, elevated suicide risk, active eating disorder, cognitive impairment, harmful substance use, or recent regular meditative movement practice are unlikely to benefit from this pilot.
Why it matters
Potential benefit: If successful, the program could provide a low‑risk, non‑drug option to help manage upper GI symptoms and improve patient quality of life.
How similar studies have performed: Seated yoga and mind–body approaches have shown promise for symptom management in some GI and oncology settings, but this specific brain–gut adaptation for FD and gastroparesis is largely untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years and older * Functional Dyspepsia or Gastroparesis (FP or GP) diagnosed by a physician using standard criteria * Signed, written consent Exclusion Criteria: * Co-morbid Gastrointestinal or related disorders documents in the medical record: celiac disease, inflammatory Bowel Disease(active), gastrointestinal obstruction (if current in the last 6 months), any GI surgery within the last 6 months), chronic pancreatitis or any pancreatic or biliary disease, cirrhosis or any chronic liver disease other than metabolic associated hepatic disease (MASH), any malignancy (except skin cancer already resected and surgically in remission) * A positive screen for the following: current psychotic symptoms, elevated suicide risk, active eating disorder, cognitive impairment, current harmful alcohol or substance use * Does not understand English * Underwent a regular yoga or other mediative movement practice (tai chi or qi gong) in the past 6 month
Where this trial is running
Charlotte, North Carolina
- Atrium Health Gastroenterology and Hepatology Kenilworth — Charlotte, North Carolina, United States (Recruiting)
Study contacts
- Principal investigator: Elyse Thakur, MD — Wake Forest University
- Study coordinator: Jessica Kearney-Bryan, BSN
- Email: jessica.kearney-bryan@advocatehealth.org
- Phone: 704-355-0244
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.