Screening for Rheumatic Heart Disease in Rural Communities
Official title: Screening and Secondary Prevention Rheumatic Heart Disease
Run by National Institute of Cardiovascular Diseases, Pakistan · NCT05991219 · Data updated 2026-11-12
This study is testing if using ultrasound to screen for Rheumatic Heart Disease in rural communities can help find and treat the condition early to improve health outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 10 Years to 30 Years |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | National Institute of Cardiovascular Diseases, Pakistan Academic / other |
| Locations | 1 site (Karachi, Sindh) |
| Status | Recruiting |
| Started | September 26, 2022 |
| Main results expected | December 31, 2028 |
| Study ends | December 31, 2028 |
| Registry record updated | August 15, 2023 |
| Trial ID | NCT05991219 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals living in rural communities in Sindh who are at risk for Rheumatic Heart Disease.
✕Probably not a fit
Patients who refuse to participate in the study will not receive any benefit from the interventions offered.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on screening for Rheumatic Heart Disease (RHD) in rural communities of Sindh using point of care ultrasound to assess heart valve conditions. Patients diagnosed with RHD will receive tailored treatment and referrals based on the severity of their condition. The study aims to implement community health worker-led antibiotic prophylaxis to prevent disease progression, with follow-up imaging scheduled at two and five years to evaluate outcomes. The goal is to identify and manage RHD early to improve patient outcomes in a cost-effective manner.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the progression of Rheumatic Heart Disease and improve long-term heart health for affected patients.
How similar studies have gone: Other studies have shown success in using point of care ultrasound for early detection and management of Rheumatic Heart Disease, indicating that this approach is promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Rural communities in Sindh Exclusion Criteria: * Refused to participate in the study
Where it's running
-
National Institute of Cardiovascular Diseases (NICVD)
Karachi, Sindh, Pakistan Recruiting
Study contacts
- Principal investigator: Sabha Bhatti, MD — National Institute of Cardiovascular Diseases
- Study coordinator: Sabha Bhatti, MD
- Email: drsabhabhatti@gmail.com
- Phone: +92 335 5554346
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.