Screening for Advanced Liver Fibrosis with Simple Blood Tests in Primary Care

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational effort evaluates sequential liver fibrosis screening using the FIB-4 score as a first step, followed by a specialized fibrosis test for confirmation. It is conducted in the Grenoble area with Biogroup Laboratories and the Hepato-gastroenterology department at Grenoble University Hospital. Eligible adults aged 18 to 70 with a FIB-4 score of 2.67 or higher and with health insurance are invited to participate. The study excludes individuals whose FIB-4 was ordered by a specialist for a specific condition or who have factors that may falsely elevate the FIB-4, among other criteria. The goal is to assess how successfully this screening approach can identify asymptomatic patients with advanced hepatic fibrosis in a real-world setting.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients between 18 and 70 years of age
* FIB-4 2.67
* Patients covered by Health Insurance System

Exclusion Criteria:

* Prescription triggering FIB-4 emanate from a hepatogastroenterologist or oncologist
* Conditions associated with high risk false-positive FIB-4: ASAT or ALAT \> 300 IU/L, platelets \<50 G/L or \>500 G/L.
* Patient refusing to participate
* Subjects under guardianship or deprived of liberty

Where it's running

• CHU Grenoble Alpes
  Grenoble, France Recruiting

Study contacts

• Study coordinator: Charlotte Costentin, Pr
• Email: ccostentin@chu-grenoble.fr
• Phone: +33476769368

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.