Screening children and parents for familial hypercholesterolemia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to implement a child-parent screening program for familial hypercholesterolemia (FH) to identify children and their parents who are carriers of FH mutations and at high risk for premature coronary artery disease. The study will involve a community-based screening of children aged 2 years, starting with a finger blood total cholesterol test, followed by further testing for those with elevated cholesterol levels. The goal is to establish effective screening techniques and protocols for early diagnosis and intervention in FH families.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Receive routine child care
* aged 1 - 3 years old ( date of investigate minus date of birth)

Exclusion Criteria:

* It is up to the researcher to decide whether it is suitable to participate in this research

Where it's running

• Anhui Provincial Children's Hospital
  Hefei, Anhui, China Recruiting
• Qidong Women and Children Hospital
  Qidong, Jiangsu, China Recruiting
• Weili Yan
  Shanghai, Shanghai Municipality, China Recruiting
• Shanxi Provincial Children's Hospital
  Taiyuan, Shanxi, China Recruiting
• Chongqin Medical University Affiliated Children's Hospital
  Chongqing, Sichuan, China Recruiting
• Urumqi Children's Hospital
  Ürümqi, Xinjiang, China Recruiting

Study contacts

• Study coordinator: Weili Yan
• Email: yanwl@fudan.edu.cn
• Phone: +86 21 64931215

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• ORIGIN-FH: Newborn screening to detect familial high cholesterol

  This project will test a genetic cheek swab of parents plus blood screening of newborns to find familial high cholesterol in babies born to parents with familial hypercholesterolemia.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07470723

• Registry for hereditary cardiovascular diseases in Brazil

  This study is trying to create a registry of Brazilian patients with hereditary heart diseases to see how common certain genetic changes are in people with these conditions.

  Recruiting at 27 sites Hospital do Coracao · Rio Branco, Acre and 26 other locations · NCT06546137

• Exploring YOLT-101 for treating Familial Hypercholesterolemia

  This study is testing a new treatment called YOLT-101 to see if it can safely lower cholesterol levels in people with familial hypercholesterolemia.

  Recruiting Early Phase 1 RenJi Hospital · Shanghai, Shanghai Municipality · NCT06458010

• Atlantic program to optimize cholesterol-lowering care

  This program will try coordinated outreach with primary care providers to lower LDL-C in people with familial hypercholesterolemia or LDL-C ≥160 mg/dL.

  Recruiting Atlantic Health System · Clark, New Jersey and 1 other locations · NCT06439654

• Observational study on genetic lipid disorders in Italy

  This study looks at families with high cholesterol to see how genetics affect their condition and treatment, using information gathered during regular doctor visits.

  Recruiting Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) · Sesto San Giovanni, Milano · NCT06362473

• Improving detection of familial hypercholesterolemia through lab comments on cholesterol levels

  This study is testing if adding helpful comments about high cholesterol levels in lab reports can lead to more people being referred for familial hypercholesterolemia diagnosis and treatment in Southern Denmark.

  Recruiting at 2 sites Odense University Hospital · Odense, Funen and 1 other locations · NCT05614219

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.