Observational study on genetic lipid disorders in Italy
Lipid Transport Disorder Italian Genetic Record (LIPIGEN)
This study looks at families with high cholesterol to see how genetics affect their condition and treatment, using information gathered during regular doctor visits.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Sex | All |
| Sponsor | Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) Academic / other |
| Locations | 1 site (Sesto San Giovanni, Milano) |
| Trial ID | NCT06362473 on ClinicalTrials.gov |
What this trial studies
LIPIGEN is an observational study that involves Italian physicians and researchers focusing on familial dyslipidaemias, particularly familial hypercholesterolaemia (FH). The study collects data from patients during their routine clinical examinations without introducing additional procedures. It aims to enhance the understanding of FH and related conditions by examining clinical diagnoses, genetic testing, and treatment effectiveness. The research also seeks to identify genetic mutations responsible for these disorders to inform more effective treatment strategies.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with a molecular or clinical diagnosis of genetic dyslipidemia.
Not a fit: Patients without a diagnosis of genetic dyslipidemia will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and treatment options for patients with familial hypercholesterolaemia and other genetic lipid disorders.
How similar studies have performed: Other studies focusing on genetic dyslipidemias have shown promise, but this specific observational approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Molecular or clinical diagnosis of genetic dyslipidemia * Informed consent signed Exclusion Criteria: * None
Where this trial is running
Sesto San Giovanni, Milano
- IRCCS Multimedica — Sesto San Giovanni, Milano, Italy (Recruiting)
Study contacts
- Study coordinator: Manuela Casula, PhD
- Email: manuela.casula@unimi.it
- Phone: 0039 + 0250318428
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.