Sciatic nerve stiffness during two lower-limb neurodynamic movement sequences measured with shear wave elastography.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will use shear wave elastography (SWE) while performing two sequences of the lower limb neurodynamic test (proximal-to-distal and distal-to-proximal) to measure sciatic nerve stiffness. Thirty adults aged 25–40 with low back pain and unilateral leg pain (sciatica) and thirty asymptomatic controls will undergo SWE measurements during each LLNT sequence. The study will compare within-participant changes in shear-wave velocity between sequences and between the sciatica and control groups. Results aim to clarify how neurodynamic sequencing redistributes neural load and whether sequence-dependent stiffness differences can improve localization of sciatic nerve pathology.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Thirty participants ranging in age from 25 to 40 years from both genders with a diagnosis of low back pain with radiating leg pain and thirty control group.
* The main symptoms are low back pain with unilateral leg pain(sciatica) for 3-12 months for group A.
* Patients with lumbar disc herniation (L4-5) with diagnostic imaging as MRI for group A.
* Positive straight leg raising are considered for inclusion in the study for group A.
* Control group must be free from any symptoms of nerve irritation or compression, with normal neurological examination findings, including reflexes, sensation, negative straight leg raising and motor strength.

Exclusion Criteria:

* Diabetes mellitus.
* Any type of polyneuropathy
* Trauma of lumbar spine
* Previous history of back surgery
* Piriformis syndrome.
* Participants with conditions that reduce image quality on US imaging (thick gluteal subcutaneous fat tissue.
* Hip joint prosthesis.
* Professional athletes (Neto et al., 2024).
* Skin infection

Where it's running

• Cairo University
  Giza, Egypt Recruiting

Study contacts

• Study coordinator: Manar Fawzy Mohammed Hussein, M.Sc
• Email: manar.fawzy@the.suezuni.edu.eg
• Phone: +20 120 140 8924

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.