Checking whether an adductor canal injection spreads to the tibial and fibular branches of the sciatic nerve.
Official title: Evaluation of Local Anesthetic Diffusion to the Sciatic Nerve During Adductor Canal Block: an Observational Study
Run by Assistance Publique - Hôpitaux de Paris · NCT07301476 · Data updated 2026-11-12
For adults having elective knee surgery with an adductor canal block, this will test if the local anesthetic spreads to the tibial and fibular branches of the sciatic nerve.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Boulogne-Billancourt) |
| Status | Recruiting |
| Started | December 10, 2025 |
| Main results expected | December 2027 |
| Study ends | December 2027 |
| Registry record updated | December 24, 2025 |
| Trial ID | NCT07301476 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (over 18) scheduled for elective knee surgery at the participating center who will receive an adductor canal block and meet the study's inclusion/exclusion criteria are eligible.
✕Probably not a fit
Patients with existing lower-limb peripheral neuropathy, those who receive additional blocks or surgical infiltration, or those not treated at the study center are unlikely to gain useful information from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-center observational study will enroll adults scheduled for elective knee surgery who receive a standard adductor canal block at CHU Raymond Poincaré (AP-HP). After the block, investigators will perform clinical sensorimotor testing to detect signs of tibial and fibular nerve involvement attributed to local anesthetic spread through the adductor hiatus. The primary outcome is the frequency of clinical diffusion to the tibial and fibular nerves. Patients with peripheral neuropathy, additional lower-limb blocks (such as IPACK), or other exclusion criteria are not eligible.
Why it matters
Potential benefit: If successful, the results could help clinicians predict when an adductor canal block will provide broader sciatic-nerve coverage and guide pain-control planning after knee surgery.
How similar studies have gone: Prior anatomical and imaging reports have suggested that adductor canal injections can spread to tibial and fibular nerves via the adductor hiatus, but no clinical study has measured how often this occurs.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients over 18 years old scheduled for elective knee surgery under general anesthesia * in our center * receiving an adductor canal block Exclusion Criteria: * patients cognitively impaired, * patients suffering from peripheral neuropathy at the lower limb, * patients receiving an IPACK block or surgical knee infiltration to complete the adductor canal block analgesia. * patients who refused to take part in this study * pregnant or breastfeeding patients * patients under guardianship * imprisoned patients, * patients without any medical insurance
Where it's running
-
Department of Anesthésia, CHU Raymond Poincaré - APHP
Boulogne-Billancourt, France Recruiting
Study contacts
- Principal investigator: Romuald Henry, MD — CHU Raymond Poincaré - APHP
- Study coordinator: Romuald Henry, MD
- Email: romuald.henry@aphp.fr
- Phone: + 33 06 72 83 17 51
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.