Sage Extract and Memory in Middle-Aged Adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study will give SageXtra or placebo daily for eight weeks to middle-aged men and women. The trial will measure cognitive function and psychomotor performance to see if sage extract affects cognitive abilities and reaction times. Participants will maintain their usual diet and avoid alcohol, caffeine, and strenuous exercise for testing sessions. The study is sponsored by ESM Technologies with collaboration from Texas A&M University’s Exercise & Sport Nutrition Lab.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* BMI 18.5-34.9 (inclusive) with a goal of being \< 30 on average
* Subject agrees to maintain their existing dietary patterns throughout the study period.
* Subject agrees to refrain from alcohol, caffeine, and strenuous exercise for 24 hours before each test day.
* Subject is willing and able to comply with the study protocol.
* Has given voluntary, written, informed consent to participate in the study.

Exclusion Criteria:

* Individuals with a personal history of a psychiatric disorder.
* Individuals who are determined to have liver, renal, cardiovascular, or other metabolic disease.
* Current or recent (\< 4 weeks) use of any dietary supplements (e.g., choline, lecithin, ginseng, ginkgo biloba, ashwagandha, Bacopa Monnieri, Paullina cupana, Rhodiola rosea, L-theanine, omega-3 fats, Prevagen, etc.), or currently prescribed medications (e.g., Adderall, Mydayis, Ritalin, Concerta, Mythylin, Provigil, Namenda), that may affect cognitive function (focus, concentration, memory, reaction time, energy, etc.).
* Alcohol consumption (\>2 standard alcoholic drinks/day or \>10 drinks/week) or drug abuse/dependence (including regular marijuana or THC use).
* Currently a smoker.
* Allergy or sensitivity to study product ingredients.
* Individuals who are cognitively impaired and/or who are unable to give informed consent.
* Any other condition which, in the PI's opinion, may adversely affect the subject's ability to complete the study, its measurements, or pose a significant risk to the subject.

Where it's running

• Exercise & Sport Nutrition Lab - Texas A&M University
  College Station, Texas, United States Recruiting

Study contacts

• Study coordinator: Richard B. Kreider, Ph.D.
• Email: rbkreider@tamu.edu
• Phone: (979) 458-1498

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.