Robotic treatment for urinary symptoms in older men

AQUABEAM® Robotic System and Ultrasound Accessories (AQUA Study)

Not applicable Interventional Centre hospitalier de l'Université de Montréal (CHUM) · NCT05157529

This study is testing a new robotic treatment to see if it can help older men with urinary problems caused by an enlarged prostate.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years and up
SexMale
SponsorCentre hospitalier de l'Université de Montréal (CHUM) Academic / other
Locations1 site (Montreal, Quebec)
Trial IDNCT05157529 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of the AQUABEAM Robotic System combined with ultrasound technology for treating lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH). The AQUABEAM system uses a precise water jet to ablate prostate tissue, aiming to relieve bladder outlet obstruction. The study includes men aged 65 and older who experience moderate to severe LUTS and are willing to participate in the trial. Participants will be monitored for their response to the treatment and any associated outcomes.

Who should consider this trial

Good fit: Ideal candidates are older men diagnosed with LUTS due to BPH who can comply with study protocols.

Not a fit: Patients who are unable to stop anticoagulants or have contraindications for anesthesia may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could significantly improve the quality of life for older men suffering from urinary symptoms related to BPH.

How similar studies have performed: Other studies have shown promising results with robotic and minimally invasive approaches for treating BPH, suggesting potential for success with this novel method.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* a) Patient has diagnosis of LUTS due to BPH
* b) Patient is mentally capable and willing to sign a study-specific informed consent form
* c) Patient is able and willing to follow study instructions and likely to attend and complete all required study visits

Exclusion Criteria:

* a) Patient is unable to stop anticoagulants, antiplatelet agents, or non-steroidal anti- inflammatory agents (NSAIDs, including aspirin greater or equal to 100mg) prior to treatment per standard of care
* b) Contraindications for general and spinal anesthesia
* c) Patient is unwilling to accept a blood transfusion if required

Where this trial is running

Montreal, Quebec

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Benign Prostatic HyperplasiaLower Urinary Tract Symptoms
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.