Rewards for abstaining from cannabis use

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness and cost-effectiveness of contingency management (CM) compared to cognitive behavioral therapy (CBT) for treating cannabis use disorder (CUD) in youths aged 16-22. Participants will be randomly assigned to either 12 weeks of outpatient CM or CBT, with assessments conducted at multiple time points to evaluate cannabis abstinence and treatment outcomes. The study aims to determine which approach leads to more days of abstinence and is more cost-effective over a 12-month follow-up period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Youths (16-22 years) seeking treatment for a primary CUD
* Regular cannabis use (≥14 days) in past 4 weeks
* Intention to cease cannabis use during intervention
* Able and willing to attend the treatment center and submit urine samples under supervision twice-weekly
* Informed consent.

Exclusion Criteria:

* Health contra-indications (e.g., acute psychosis/suicidality)
* Insufficient Dutch language.

Where it's running

• Jellinek, Stichting Arkin B.V.
  Amsterdam, Netherlands Recruiting
• IrisZorg
  Arnhem, Netherlands Recruiting
• Antes Youz
  Rotterdam, Netherlands Recruiting
• Brijder
  The Hague, Netherlands Recruiting
• Novadic-Kentron
  Vught, Netherlands Recruiting

Study contacts

• Principal investigator: Renske Spijkerman, PhD — Parc
• Study coordinator: Eva Garssen, MsC
• Email: e.garssen@brijder.nl
• Phone: +3188 358 20 34

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Can tACS modulate motivation and reward signals in cannabis use disorder and depression

  We’re testing whether a gentle brain stimulation method (tACS) can boost motivation and reward responses in adults with cannabis use and/or depression to see if it helps with anhedonia.

  Recruiting Florida State University · Tallahassee, Florida and 1 other locations · NCT07924852

• Sex differences in how cannabis affects people who regularly use it

  This Phase 2 trial tests whether men and women who use cannabis several days a week respond differently to THC versus placebo.

  Recruiting Phase 2 Medical University of South Carolina · Charleston, South Carolina · NCT07815691

• Semaglutide for cannabis use disorder: see if a medicine helps reduce use

  This study tests whether weekly injections of semaglutide can help adults with cannabis use disorder reduce their cannabis use compared with placebo.

  Recruiting Phase 2 Psychiatric Centre Rigshospitalet · Frederiksberg · NCT07523633

• Brain imaging to predict teens' response to cannabis treatment

  This project will test whether teens' brain activity during a learning task can predict how well 14–17-year-olds do in a 10-week virtual reward program to reduce cannabis use.

  Recruiting Indiana University · Indianapolis, Indiana · NCT07340554

• Reducing cannabis use to improve daily functioning.

  This program will try an 8-week combination of motivational interviewing, computerized CBT (CBT4CBT), and small financial rewards to help adults with cannabis use disorder cut back on cannabis.

  Recruiting Medical University of South Carolina · Charleston, South Carolina · NCT07218471

• Home-based brain stimulation with guided mindfulness for cannabis use disorder

  This project tests whether daily at-home mild brain stimulation plus guided mindfulness can help adults with cannabis use disorder reduce or stop their cannabis use.

  Recruiting NYU Langone Health · New York, New York · NCT07184983

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.