Remineralizing with nano-eggshell varnish, CPP-ACP paste, or fluoride varnish in teens with early tooth decay

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized, three-arm study, adolescents aged 15 to 20 with initial enamel caries are assigned to nano-eggshell varnish, CPP-ACP paste, or sodium fluoride varnish. Remineralization and caries activity will be tracked over 12 months using DIAGNOdent readings, ICCMS criteria, and the DMFS index. The aim is to compare the effectiveness of each treatment in reducing caries progression and promoting remineralization. Participants are assessed at multiple time points to determine changes in lesion status and overall dental health. The study is conducted at Mansoura University’s Faculty of Dentistry with a lead sponsor and no listed collaborators.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients' ages should be 15-20 years. Patients should have at least three to four teeth with ICDAS II scores of 1-2. Patients should have moderate-to-high caries risk.

Exclusion Criteria:

Known hypersensitivity to one of the components of the material under study. Systemic disorders or medication interfering with normal salivary flow.

Where it's running

• Faculty of Dentistry, Mansoura University
  Al Mansurah, Egypt Recruiting

Study contacts

• Study coordinator: Ghada E Elhindawy
• Email: ghada.ezzat91@yahoo.com
• Phone: 00201102668577

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.