Rehabilitation program for speech improvement in post-stroke aphasia patients

Evaluation of an Enriched Speech Rehabilitation Program Combining Speech Therapy and Sensory-motor Integration in Aphasic Patients

Not applicable Interventional University Hospital, Grenoble · NCT04433351

This study is testing a new speech therapy program using a special device to help stroke patients with speech difficulties improve their communication skills better than traditional methods.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment36 (estimated)
Ages55 Years to 75 Years
SexAll
SponsorUniversity Hospital, Grenoble Academic / other
Locations1 site (Grenoble)
Trial IDNCT04433351 on ClinicalTrials.gov

What this trial studies

This project aims to develop and test a novel speech rehabilitation program for patients with non-fluent aphasia following a stroke. The approach utilizes an innovative device called Ultraspeech, which enhances the interaction between perceptual and motor representations of speech. Patients will engage in exercises that involve visualizing the movements of a healthy speaker's tongue and lips while practicing their own speech production. The study will compare the effectiveness of this enriched rehabilitation program against traditional speech therapy methods. The goal is to better understand neural reorganization associated with recovery.

Who should consider this trial

Good fit: Ideal candidates are native French speakers with non-fluent aphasia due to a dominant hemisphere stroke.

Not a fit: Patients with comprehension deficits, hemi-spatial neglect, or upper limb apraxia may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly improve speech capabilities in patients suffering from non-fluent aphasia.

How similar studies have performed: Other studies have shown promise in using sensory-motor integration techniques for speech rehabilitation, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients with non-fluent aphasia after lesion in the dominant hemisphere for language
* native speakers of French
* normal or corrected to normal vision
* satisfying all criteria for the MRI examination

Exclusion Criteria:

* patients with comprehension deficits, hemi-spatial neglect or upper limb apraxia

Where this trial is running

Grenoble

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Aphasia Non FluentStrokepost-stroke aphasianon-fluent aphasiaspeech rehabilitationneuroimagingneural reorganizationrecovery
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.