Rehabilitation program for speech improvement in post-stroke aphasia patients
Official title: Evaluation of an Enriched Speech Rehabilitation Program Combining Speech Therapy and Sensory-motor Integration in Aphasic Patients
Run by University Hospital, Grenoble · NCT04433351 · Data updated 2026-11-12
This study is testing a new speech therapy program using a special device to help stroke patients with speech difficulties improve their communication skills better than traditional methods.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 55 Years to 75 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | University Hospital, Grenoble Academic / other |
| Locations | 1 site (Grenoble) |
| Status | Recruiting |
| Started | May 5, 2022 |
| Main results expected | May 5, 2028 |
| Study ends | May 5, 2028 |
| Registry record updated | October 2, 2026 |
| Trial ID | NCT04433351 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are native French speakers with non-fluent aphasia due to a dominant hemisphere stroke.
✕Probably not a fit
Patients with comprehension deficits, hemi-spatial neglect, or upper limb apraxia may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project aims to develop and test a novel speech rehabilitation program for patients with non-fluent aphasia following a stroke. The approach utilizes an innovative device called Ultraspeech, which enhances the interaction between perceptual and motor representations of speech. Patients will engage in exercises that involve visualizing the movements of a healthy speaker's tongue and lips while practicing their own speech production. The study will compare the effectiveness of this enriched rehabilitation program against traditional speech therapy methods. The goal is to better understand neural reorganization associated with recovery.
Why it matters
Potential benefit: If successful, this program could significantly improve speech capabilities in patients suffering from non-fluent aphasia.
How similar studies have gone: Other studies have shown promise in using sensory-motor integration techniques for speech rehabilitation, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients with non-fluent aphasia after lesion in the dominant hemisphere for language * native speakers of French * normal or corrected to normal vision * satisfying all criteria for the MRI examination Exclusion Criteria: * patients with comprehension deficits, hemi-spatial neglect or upper limb apraxia
Where it's running
-
Chu Grenoble Alpes
Grenoble, France Recruiting
Study contacts
- Principal investigator: Monica Baciu, MD PhD — University Hospital, Grenoble & Laboratoire de Psychologie et NeuroCognition
- Study coordinator: University Hospital, Grenoble
- Email: tmontagnon@chu-grenoble.fr
- Phone: 04 76 76 68 14
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.