Rehabilitation and education for airway clearance in patients with NTM-PD
Rehabilitation Exercise and Education of Airway Clearance Technique in Nontuberculous Mycobacterial Pulmonary Disease: A Prospective Cohort Study
This study is testing if an 8-week program of lung exercises and education can help adults with nontuberculous mycobacterial pulmonary disease breathe better and feel healthier.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | Seoul National University Bundang Hospital Academic / other |
| Locations | 1 site (Seongnam-si, Gyeonggi-do) |
| Trial ID | NCT06838442 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the effects of pulmonary rehabilitation and airway clearance education in adults diagnosed with nontuberculous mycobacterial pulmonary disease (NTM-PD). Participants will undergo an 8-week program consisting of biweekly sessions focused on improving lung function, symptom relief, and quality of life. The study will assess outcomes through various evaluations, including pulmonary function tests, symptom assessments, and quality of life surveys, at multiple time points throughout the intervention and follow-up. The goal is to determine if this non-pharmacological approach can enhance sputum culture conversion rates and overall patient well-being.
Who should consider this trial
Good fit: Ideal candidates are adults aged 20 years or older with a confirmed diagnosis of NTM-PD who can participate in rehabilitation.
Not a fit: Patients who are pregnant, breastfeeding, or have severe mobility impairments may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve lung function and quality of life for patients with NTM-PD.
How similar studies have performed: Other studies have shown positive outcomes with similar rehabilitation approaches in pulmonary diseases, suggesting potential for success in this context.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 20 years or older at the time of enrollment. * Diagnosis of nontuberculous mycobacterial pulmonary disease (NTM-PD) according to the 2020 American Thoracic Society (ATS) guidelines. * Identification of clinically significant NTM species, including: Mycobacterium avium / Mycobacterium intracellulare / Mycobacterium abscessus / Mycobacterium massiliense / Mycobacterium kansasii / * Able to undergo pulmonary rehabilitation and airway clearance training as part of the study protocol. * Willing to provide written informed consent to participate in the study. Exclusion Criteria: * Currently pregnant or actively breastfeeding. * Unable to participate in pulmonary rehabilitation due to severe mobility impairment or neuromuscular disorders. * History of massive hemoptysis or other medical conditions where airway clearance techniques may be contraindicated.
Where this trial is running
Seongnam-si, Gyeonggi-do
- Seoul National University Bundang Hospital — Seongnam-si, Gyeonggi-do, South Korea (Recruiting)
Study contacts
- Study coordinator: Hyung-Jun Kim, MD
- Email: dr.hjkim@snu.ac.kr
- Phone: +82-31-787-7844
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.