Registry of patients with familial hypercholesterolemia in Spain
Official title: The Spanish Familial Hypercholesterolaemia Cohort Study
Run by Fundación Hipercolesterolemia Familiar · NCT02693548 · Data updated 2026-11-12
This study is collecting information from people in Spain with a genetic condition called familial hypercholesterolemia to better understand their health and how they respond to treatments.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 15 Years and up |
| Sex | All |
| Enrollment | 4141 (estimated) |
| Sponsor | Fundación Hipercolesterolemia Familiar Academic / other |
| Locations | 1 site (Madrid, Madrid) |
| Status | Recruiting |
| Started | January 2004 |
| Main results expected | October 2030 |
| Study ends | October 2030 |
| Registry record updated | September 4, 2026 |
| Trial ID | NCT02693548 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals over 15 years old with a genetic diagnosis of heterozygous familial hypercholesterolemia and their first-degree relatives.
✕Probably not a fit
Patients who are unwilling to participate or do not have a genetic diagnosis of familial hypercholesterolemia will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The SAFEHEART project is an ongoing observational registry that focuses on patients with genetically confirmed heterozygous familial hypercholesterolemia (FH) in Spain. This study aims to gather comprehensive data on the clinical characteristics, treatment responses, and outcomes of these patients, who are at high risk for severe cardiovascular diseases. By analyzing the genetic mutations associated with FH and their impact on health, the study seeks to improve understanding and management of this condition. The registry includes index cases and their first-degree relatives, providing a broad perspective on familial patterns of FH.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies and outcomes for patients with familial hypercholesterolemia.
How similar studies have gone: Previous studies on familial hypercholesterolemia have shown significant advancements in understanding and treating the condition, indicating that this approach is built on established research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Index cases with genetic diagnosis of FH and their relatives over 15 years old with a genetic diagnosis of FH and their first-degree relatives Exclusion Criteria: * Patient unwillingness
Where it's running
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Fundacion Hipercolesterolemia Familiar
Madrid, Madrid, Spain Recruiting
Study contacts
- Study coordinator: Pedro Mata, MD
- Email: pmata@colesterolfamiliar.org
- Phone: 0034915570071
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Cardiovascular health in children and young adults with chronic conditions
This project will see if children and young adults (ages 6-25) with chronic health conditions show early signs of aging in large and small blood vessels using noninvasive imaging and clinical tests.
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Computer alert to help identify and manage familial high cholesterol
This project will test whether a computer alert in the electronic health record helps clinicians recognize and treat adults with familial hypercholesterolemia.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.