Clinical trial Recruiting at 1 site Observational

Registry of Parkinson's disease patients with SNCA gene variants in China

Official title: The Chinese Parkinson's Disease With SNCA Variants Registry

Run by Xiangya Hospital of Central South University · NCT03523052 · Data updated 2026-11-12

This study is trying to gather information from people with Parkinson's disease in China who have certain gene changes to better understand how these changes affect their symptoms and the disease's progression.

More Parkinson Disease trials

Quick facts

Study typeObservational
SexAll
Enrollment3000 (estimated)
SponsorXiangya Hospital of Central South University
Academic / other
Locations1 site (Changsha, Hunan)
StatusRecruiting
StartedFebruary 1, 2017
Main results expectedFebruary 1, 2027
Study endsFebruary 1, 2027
Registry record updatedMay 29, 2018
Trial IDNCT03523052 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients diagnosed with Parkinson's disease who have tested positive for SNCA gene variants.

Probably not a fit

Patients without a diagnosis of Parkinson's disease or those who do not have SNCA gene variants may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Chinese PD-SNCA Registry aims to create a comprehensive database of patients diagnosed with Parkinson's disease who have specific variants of the SNCA gene. This observational study will collect peripheral blood samples from participants to identify SNCA gene variants and assess their clinical manifestations using various standardized neurological scales and tests. Additionally, the study will analyze blood biomarkers associated with Parkinson's disease to better understand the condition's progression and characteristics in the Chinese population.

Why it matters

Potential benefit: If successful, this registry could enhance understanding of Parkinson's disease and lead to improved diagnosis and treatment strategies for patients with SNCA gene variants.

How similar studies have gone: While the study focuses on a specific genetic variant in a defined population, similar registries have shown promise in enhancing understanding of genetic influences on Parkinson's disease.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients diagnosed with PD by the United Kingdom Parkinson's Disease Society Brain Bank clinical diagnostic criteria or other standard criteria; PD patients detected with positive SNCA variants

Exclusion Criteria:

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Where it's running

  • Xiangya Hospital of Central South University
    Changsha, Hunan, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.