Registry of Parkinson's disease patients with LRRK2 gene variants in China
Official title: The Chinese Parkinson's Disease With LRRK2 Variants Registry
Run by Xiangya Hospital of Central South University · NCT03523104 · Data updated 2026-11-12
This study is creating a database to learn more about Parkinson's disease in people with specific LRRK2 gene changes in China by collecting health information and blood samples.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Xiangya Hospital of Central South University Academic / other |
| Locations | 1 site (Changsha, Hunan) |
| Status | Recruiting |
| Started | February 1, 2017 |
| Main results expected | February 1, 2027 |
| Study ends | February 1, 2027 |
| Registry record updated | May 29, 2018 |
| Trial ID | NCT03523104 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this registry are patients diagnosed with Parkinson's disease who have tested positive for LRRK2 gene variants.
✕Probably not a fit
Patients without a diagnosis of Parkinson's disease or those who do not have LRRK2 gene variants may not benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The Chinese PD-LRRK2 Registry aims to create a comprehensive database of patients diagnosed with Parkinson's disease (PD) who have specific LRRK2 gene variants. This observational study will collect clinical data and assess the manifestations of PD using various standardized scales and neurological tests. Additionally, blood samples will be analyzed for biomarkers associated with PD, such as uric acid and inflammatory markers. The goal is to better understand the clinical characteristics of PD patients with LRRK2 variants in mainland China.
Why it matters
Potential benefit: If successful, this registry could enhance understanding of Parkinson's disease and improve personalized treatment strategies for patients with LRRK2 gene variants.
How similar studies have gone: While there have been studies on LRRK2 variants in Parkinson's disease, this registry approach is relatively novel in the context of mainland China.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients diagnosed with PD by the United Kingdom Parkinson's Disease Society Brain Bank clinical diagnostic criteria or other standard criteria; PD patients detected with positive LRRK2 variants Exclusion Criteria: \-
Where it's running
-
Xiangya Hospital of Central South University
Changsha, Hunan, China Recruiting
Study contacts
- Study coordinator: Jifeng Guo, Ph.D.
- Email: guojifeng2003@163.com
- Phone: +8613974936815
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.