Registry of outcomes for patients with advanced thyroid cancer

Global Real World Data in Patients With Advanced Thyroid Cancer on Standard of Care and Specialized Interventions- Registry of Oncologic Outcomes With Testing and Treatment.

Observational M.D. Anderson Cancer Center · NCT06507878

This study looks at how well different treatments work for people with advanced thyroid cancer, comparing those treated at MD Anderson Cancer Center to those treated elsewhere, while also checking how these treatments affect their quality of life.

Quick facts

Study typeObservational
Enrollment459 (estimated)
Ages18 Years and up
SexAll
SponsorM.D. Anderson Cancer Center Academic / other
Drugs / interventionschemotherapy, immunotherapy, radiation
Locations1 site (Houston, Texas)
Trial IDNCT06507878 on ClinicalTrials.gov

What this trial studies

This observational study aims to gather real-world data on patients with advanced thyroid cancer, focusing on their access to treatments and how they respond to commercially available medications outside of clinical trials. The primary objective is to compare overall survival between patients treated at MD Anderson Cancer Center and those treated elsewhere, based on their BRAF status and disease stage. Additionally, the study will evaluate the impact of various therapies on the quality of life of survivors and how sociodemographic factors influence patient outcomes.

Who should consider this trial

Good fit: Ideal candidates include adult patients aged 18 years or older diagnosed with anaplastic thyroid cancer or poorly differentiated thyroid cancer.

Not a fit: Patients without a diagnosis of anaplastic or poorly differentiated thyroid cancer will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve understanding of treatment access and effectiveness for advanced thyroid cancer, leading to better patient outcomes.

How similar studies have performed: Other studies have shown success in gathering real-world data for cancer treatments, indicating that this approach is promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

All adult patients aged 18 years or older (with the exception of certain external participant countries where the legal adult age may be different; for example in Singapore, adult majors are defined by age 21 and older) with anaplastic thyroid cancer or poorly differentiated thyroid cancer as their clinical and/ or histological diagnosis will be included.

Exclusion Criteria:

Patients who do not have anaplastic thyroid cancer or poorly differentiated thyroid cancer on their tumor tissue would be excluded.

Where this trial is running

Houston, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Thyroid Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.