Registry for understanding how genes affect medication responses
Official title: The Texas Interprofessional Pharmacogenomics Registry and Repository
Run by Texas A&M University · NCT06726590 · Data updated 2026-11-12
This study is trying to see how your genes affect how you respond to medications, so doctors can better choose the right treatments for you, especially if you're taking several drugs or have had bad reactions to them.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 3000 (estimated) |
| Sponsor | Texas A&M University Academic / other |
| Locations | 1 site (Bryan, Texas) |
| Status | Recruiting |
| Started | November 2025 |
| Main results expected | November 2029 |
| Study ends | November 2029 |
| Registry record updated | September 12, 2025 |
| Trial ID | NCT06726590 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 who are taking five or more medications or those on specific blood pressure or depression medications.
✕Probably not a fit
Patients who are admitted to hospice or decline to participate may not receive any benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This program collects genetic and health information to help doctors choose the right medications for patients. It aims to understand how genes influence the body's response to various medications, particularly for individuals taking multiple drugs or experiencing adverse drug reactions. Participants' medical histories will be monitored over a five-year period to assess the impact of personalized medication adjustments on their health. The study also seeks to influence healthcare policies regarding pharmacogenomic care.
Why it matters
Potential benefit: If successful, this could lead to more personalized and effective medication regimens for patients, improving their overall health outcomes.
How similar studies have gone: Other studies have shown promise in using pharmacogenomics to tailor medication therapies, indicating a growing interest and potential in this field.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * The study will invite patients who are eligible for PGX workup/PGX care to participate, provided they meet the following criteria: Use of five or more medications, including over the counter drugs, supplements, natural products, cannabis products, or other recreational drugs, or * Individuals taking blood pressure or depression medications, even if less than five medications. * Ability to understand and give consent. * Able to consent to donate blood and/or urine samples and buccal swabs. * Able to answer detailed questionnaires, including quarterly questionnaires about ADRs, cognitive testing such as serial mini-mental status exams, and or quality of life questions. * Able to understand that their health record and changes in health status will be followed for a five-year period and shared in deidentified form with the research community. * All genders. * Any age over 18 years. Exclusion Criteria: * Individuals admitted to hospice. * Declines to participate or interact with staff/share their medical status. * A diagnosis of Alzheimer's disease or related dementias in a medical record as this indicates a progressive, debilitating condition that impairs memory, thought processes, and functioning., * Individuals who are unable or unwilling to provide consent. * Unable to verbally communicate and comprehend English language
Where it's running
-
Texas A&M Family Care
Bryan, Texas, United States Recruiting
Study contacts
- Study coordinator: Kenneth S Ramos, MD, PhD
- Email: kramos@tamu.edu
- Phone: (713) 677-7440
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.