Understanding how environment and genes affect health
Personalized Environment and Genes Study
This study looks at how our genes and the environment around us work together to affect our health, especially for common diseases like diabetes and heart disease.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 25000 (estimated) |
| Ages | 18 Years to 120 Years |
| Sex | All |
| Sponsor | National Institutes of Health Clinical Center (CC) NIH |
| Locations | 1 site (Research Triangle Park, North Carolina) |
| Trial ID | NCT00341237 on ClinicalTrials.gov |
What this trial studies
The Personalized Environment and Genes Study (PEGS) investigates the interplay between genetic factors and environmental exposures to better understand the causes of common diseases such as diabetes, heart disease, and asthma. By integrating genetic and environmental data, the study aims to identify novel risk factors and improve disease prevention strategies. Participants will provide health and exposure information, which will be analyzed to uncover genetic susceptibilities to specific environmental factors. This observational study seeks to create a valuable resource for future environmental health research.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who can provide informed consent and are willing to participate in study-related visits.
Not a fit: Patients who are pregnant or unable to attend the required study visits may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to personalized prevention strategies that reduce the risk of common diseases based on individual genetic and environmental profiles.
How similar studies have performed: Other studies have shown success in exploring gene-environment interactions, making this approach both relevant and promising.
Eligibility criteria
Show full inclusion / exclusion criteria
* INCLUSION CRITERIA In order to be eligible for participation in this study, an individual must meet all of the following criteria: * Adults greater than or equal to 18 years of age * If female, must not be (self-reported as) pregnant. At the time of enrollment, a pregnancy test will only be done at the PI s discretion. * Able to understand and provide written informed consent * Able to come to the NIEHS Clinical Research Unit (CRU) for enrollment and study-related visits/procedures. EXCLUSION CRITERIA An individual who does not meet the inclusion criteria listed above is excluded from participation in this study.
Where this trial is running
Research Triangle Park, North Carolina
- NIEHS Clinical Research Unit (CRU) — Research Triangle Park, North Carolina, United States (Recruiting)
Study contacts
- Principal investigator: Lawrence S Kirschner, M.D. — National Institute of Environmental Health Sciences (NIEHS)
- Study coordinator: Jennifer L Emerson
- Email: niehs-pegs-info@nih.gov
- Phone: (800) 860-3804
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.