Clinical trial No longer in our active list Observational Ages 18 and up

Registry for patients with metastatic spine tumors

Official title: Metastatic Tumor Research and Outcome Network A Multicenter Prospective Registry for the Management and Outcome of Metastatic Spine Tumors

Run by AO Innovation Translation Center · NCT02830451 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is collecting information from patients with metastatic spine tumors to see how different factors affect their health and treatment outcomes.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment960 (estimated)
SponsorAO Innovation Translation Center
Academic / other
Locations25 sites (San Francisco, California and 24 other locations)
Trial IDNCT02830451 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this registry are adults aged 18 and older who have been diagnosed with a metastatic tumor of the spine.

Probably not a fit

Patients with primary tumors of the spine will not benefit from this registry.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This registry collects comprehensive data on patients diagnosed with metastatic spine tumors, including demographics, treatment history, and clinical outcomes. It aims to identify prognostic variables that influence patient-reported outcomes, morbidity, local tumor control, and overall survival. By gathering detailed information on symptoms, imaging, and treatment details, the registry seeks to enhance understanding of the disease and improve patient care.

Why it matters

Potential benefit: If successful, this registry could lead to improved treatment strategies and better quality of life for patients with metastatic spine tumors.

How similar studies have gone: Other studies focusing on registries for metastatic cancers have shown success in improving patient outcomes and understanding disease progression.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient 18 or older.
* Patient diagnosed with a metastatic tumor of the spine
* Informed consent obtained, i.e.:

  * Ability to understand the content of the patient information/ICF
  * Willingness and ability to participate in the registry according to the Registry Plan
  * Signed and dated EC/IRB approved written informed consent (if consent is required by the EC/ IRB at the registry site)

Exclusion Criteria:

• Patient diagnosed with a primary tumor of the spine.

Where it's running

  • University of California The UCSF Spine Center Department of Neurological Surgery
    San Francisco, California, United States
    Recruiting
  • Rush University Medical Center University Neurosurgery
    Chicago, Illinois, United States
    Recruiting
  • Johns Hopkins University Department of Neurosurgery / Spine Division
    Baltimore, Maryland, United States
    Recruiting
  • Harvard Medical School Department of Neurosurgery
    Boston, Massachusetts, United States
    Recruiting
  • Mayo Clinic Department of Neurosurgery
    Rochester, Minnesota, United States
    Recruiting
  • Memorial Sloan-Kettering Cancer Center
    New York, New York, United States
    Recruiting
Show 19 more locations
  • University of Rochester School of Medicine and Dentistry Department of Orthopaedic Surgery and Neurosurgery
    Rochester, New York, United States
    Recruiting
  • Penn Presbyterian Medical Center Department of Neurosurgery
    Philadelphia, Pennsylvania, United States
    Recruiting
  • The Warren Alpert Medical School of Brown university Department of Neurosurgery
    Providence, Rhode Island, United States
    Recruiting
  • The University of Texas MD Anderson Cancer Center Department of Neurosurgery
    Houston, Texas, United States
    Recruiting
  • Monash University Melbourne
    Clayton, Victoria, Australia
    Recruiting
  • Vancouver General Hospital and the University of British Columbia
    Vancouver, British Columbia, Canada
    Recruiting
  • Winnipeg Spine Program University of Manitoba Department of Surgery
    Winnipeg, Manitoba, Canada
    Recruiting
  • Toronto Western Hospital Department of Neurosurgery Division of Surgery
    Toronto, Ontario, Canada
    Recruiting
  • University of Toronto Odette Cancer Centre - T2 158 Sunnybrook Health Sciences Ccenter
    Toronto, Ontario, Canada
    Recruiting
  • McGill University Health Centre
    Montréal, Quebec, Canada
    Recruiting
  • Universitätsklinikum Carl Gustav Carus der Technischen Universität Dresden
    Dresden, Sachsen, Germany
    Recruiting
  • National Center for Spinal Disorders and Buda Health Center
    Budapest, Hungary
    Recruiting
  • Instituto Ortopedico Rizzoli Department of Oncologic and Degenerative Spine Surgery
    Bologna, Emilia-Romagna, Italy
    Recruiting
  • IRCCS Istituto Ortopedico Galeazzi Centro die Chirurgia Ortopedica Oncologica e Ricostr
    Milano, Lombardei, Italy
    Recruiting
  • Kanazawa Medical University Hospital Department of Orthopaedic Surgery
    Uchinoda, Ishikawa, Japan
    Recruiting
  • Universitair Medisch Centrum Utrecht
    Utrecht, Netherlands
    Recruiting
  • National University of Singapore Department of Orthopaedic Surgery
    Singapore, Singapore
    Recruiting
  • Universitätsspital Basel Wirbelsäulenzentrum
    Basel, Switzerland
    Recruiting
  • Westchester Medical Center Department of Neurosurgery
    Valhalla, New York, United States
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  • Registry for collecting data on periprosthetic fractures after hip and knee surgeries

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.