Registry for patients with acute ischemic stroke caused by large vessel occlusions
Official title: Triage of Patients With Acute Ischemic Stroke Due to Large Vessel Occlusions-2 (TRACK-LVO-2): an Imaging-based Patient Registry Study
Run by Tianjin Huanhu Hospital · NCT05659160 · Data updated 2026-11-12
This study is collecting information from patients with acute ischemic stroke caused by large vessel blockages to see if a special treatment works better than standard care.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Tianjin Huanhu Hospital Academic / other |
| Locations | 4 sites (Tianjin, Tianjin Municipality and 3 other locations) |
| Status | Recruiting |
| Started | November 1, 2021 |
| Main results expected | December 31, 2028 |
| Study ends | December 31, 2028 |
| Registry record updated | December 1, 2023 |
| Trial ID | NCT05659160 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older who have been diagnosed with acute ischemic stroke and confirmed large vessel occlusion.
✕Probably not a fit
Patients who do not have a confirmed diagnosis of acute ischemic stroke or large vessel occlusion may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational registry aims to collect data from patients admitted with acute ischemic stroke (AIS) due to large vessel occlusions (LVO) across multiple centers. It will compare the effectiveness of endovascular therapy (EVT) and best medical management (BMM) in treating these patients. The study will gather demographic information, imaging characteristics, and treatment outcomes to identify optimal imaging modalities for LVO detection and assess the prognosis of patients receiving different treatments. The findings are expected to enhance the understanding and management of LVO in AIS patients.
Why it matters
Potential benefit: If successful, this study could lead to improved detection and treatment strategies for patients suffering from acute ischemic stroke due to large vessel occlusions.
How similar studies have gone: Other studies have shown success in using observational registries to improve treatment outcomes for stroke patients, making this approach promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patient admitted from Jan. 1st 2018 to Jan. 1st 2028; 2. Age ≥ 18; 3. Ischemic stroke confirmed by head CT or MRI; 4. Large vessel occlusion confirmed by head CTA or MRA: intracranial internal carotid artery (ICA), middle cerebral artery (MCA M1/M2), anterior cerebral artery (ACA A1/A2), basilar artery (BA), vertebral artery (VA), and posterior cerebral artery (PCA P1/P2); 5. Patients receiving either endovascular therapy or best medical treatment; Exclusion Criteria: \- None
Where it's running
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Tianjin Medical University General Hospital
Tianjin, Tianjin Municipality, China Recruiting -
The Sencond Hospital of Tianjin Medical University
Tianjin, Tianjin Municipality, China Recruiting -
Tianjin Huanhu Hospital
Tianjin, Tianjin Municipality, China Recruiting -
Beijing University Binhai Hospital
Tianjin, Tianjin Municipality, China Recruiting
Study contacts
- Study coordinator: Ming Wei, PhD
- Email: drweiming@163.com
- Phone: 13502182903
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Intra-arterial Alteplase after successful reperfusion following mechanical thrombectomy
This trial tests whether giving a small amount of alteplase directly into the artery after a successful thrombectomy helps adults with acute ischemic stroke recover better.
-
Sevoflurane vs. Propofol for anesthesia in stroke patients undergoing clot-removal
This study tests whether sevoflurane or propofol used for anesthesia during endovascular treatment of an acute ischemic stroke affects the final brain damage and recovery.
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NeuroAiD test in mild to moderate ischemic stroke patients
This study tests whether adding MLC901 (NeuroAiD II) to standard stroke care helps adults who recently had an ischemic stroke recover better than standard care alone.
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Tenecteplase or Reteplase Bridging Before Thrombectomy in Acute Ischemic Stroke
This trial tests whether giving tenecteplase or reteplase before mechanical thrombectomy helps people with acute ischemic stroke due to large vessel occlusion, compared with doing thrombectomy alone.
-
Intra-arterial Thrombolysis After Endovascular Thrombectomy in AIS
This trial tests whether giving intra-arterial thrombolysis with tenecteplase or alteplase after endovascular thrombectomy helps improve recovery in adults with acute ischemic stroke.
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Sivelestat added to endovascular clot retrieval for acute anterior circulation stroke
This study tests whether giving sivelestat sodium alongside mechanical thrombectomy helps improve outcomes for adults with acute ischemic stroke due to large vessel occlusion.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.