Clinical trial Recruiting at 1 site Observational Ages 20 and up

Registry for cardiac PYP scans in patients with heart failure and amyloidosis in Taiwan

Official title: A Multi-center Registry for Clinical Information and 99mTc-pyrophosphate Scintigraphy in Patients With Suspected Cardiac Amyloidosis in Taiwan

Run by Far Eastern Memorial Hospital · NCT05593679 · Data updated 2026-11-12

This study is collecting and analyzing data from patients in Taiwan with heart failure and suspected cardiac amyloidosis to see if PYP scans can help diagnose the condition better than traditional methods.

More Heart Failure trials

Quick facts

Study typeObservational
Ages20 Years and up
SexAll
Enrollment1000 (estimated)
SponsorFar Eastern Memorial Hospital
Academic / other
Locations1 site (New Taipei City)
StatusRecruiting
StartedNovember 1, 2022
Main results expectedAugust 29, 2027
Study endsDecember 31, 2027
Registry record updatedJuly 29, 2024
Trial IDNCT05593679 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 20 and older with a documented diagnosis or suspicion of ATTR amyloidosis.

Probably not a fit

Patients with significant systemic diseases or those who refuse clinical follow-up may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to collect and analyze data from patients suspected or diagnosed with cardiac amyloidosis (CA) through PYP scans at medical centers in Taiwan. It will involve both retrospective and prospective data collection, focusing on patients with specific clinical signs and imaging results. The study will evaluate the quality of imaging and the correlation between clinical parameters and PYP scan results, potentially replacing invasive procedures like myocardial biopsy. The goal is to enhance understanding of CA and improve diagnostic strategies.

Why it matters

Potential benefit: If successful, this study could lead to earlier diagnosis and better treatment strategies for patients with cardiac amyloidosis.

How similar studies have gone: While there is limited large-scale clinical data on this specific approach, the use of PYP scans in diagnosing cardiac amyloidosis has shown promise in smaller studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. ≥ 20 years of age
2. Documented diagnosis or r/o of ATTR amyloidosis

Exclusion Criteria:

1. Pregnant or nursing (lactating) women.
2. Important systemic diseases (except heart disease or neurological diseases) such as liver cirrhosis, active malignant tumors, etc., with a life expectancy of less than 6 months.
3. Patient who refused clinical follow up.

Where it's running

  • Far Eastern Memorial Hospital
    New Taipei City, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.