Registry for cardiac PYP scans in patients with heart failure and amyloidosis in Taiwan
Official title: A Multi-center Registry for Clinical Information and 99mTc-pyrophosphate Scintigraphy in Patients With Suspected Cardiac Amyloidosis in Taiwan
Run by Far Eastern Memorial Hospital · NCT05593679 · Data updated 2026-11-12
This study is collecting and analyzing data from patients in Taiwan with heart failure and suspected cardiac amyloidosis to see if PYP scans can help diagnose the condition better than traditional methods.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Far Eastern Memorial Hospital Academic / other |
| Locations | 1 site (New Taipei City) |
| Status | Recruiting |
| Started | November 1, 2022 |
| Main results expected | August 29, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | July 29, 2024 |
| Trial ID | NCT05593679 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 20 and older with a documented diagnosis or suspicion of ATTR amyloidosis.
✕Probably not a fit
Patients with significant systemic diseases or those who refuse clinical follow-up may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project aims to collect and analyze data from patients suspected or diagnosed with cardiac amyloidosis (CA) through PYP scans at medical centers in Taiwan. It will involve both retrospective and prospective data collection, focusing on patients with specific clinical signs and imaging results. The study will evaluate the quality of imaging and the correlation between clinical parameters and PYP scan results, potentially replacing invasive procedures like myocardial biopsy. The goal is to enhance understanding of CA and improve diagnostic strategies.
Why it matters
Potential benefit: If successful, this study could lead to earlier diagnosis and better treatment strategies for patients with cardiac amyloidosis.
How similar studies have gone: While there is limited large-scale clinical data on this specific approach, the use of PYP scans in diagnosing cardiac amyloidosis has shown promise in smaller studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. ≥ 20 years of age 2. Documented diagnosis or r/o of ATTR amyloidosis Exclusion Criteria: 1. Pregnant or nursing (lactating) women. 2. Important systemic diseases (except heart disease or neurological diseases) such as liver cirrhosis, active malignant tumors, etc., with a life expectancy of less than 6 months. 3. Patient who refused clinical follow up.
Where it's running
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Far Eastern Memorial Hospital
New Taipei City, Taiwan Recruiting
Study contacts
- Principal investigator: Yen-Wen Wu — Far Eastern Memorial Hospital
- Study coordinator: Yen-Wen Wu
- Email: wuyw0502@gmail.com
- Phone: 886-2-8966-7000
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.