Registry for adults with plasma cell disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to create a registry for patients diagnosed with plasma cell disorders (PCDs) such as multiple myeloma and amyloidosis. Participants will complete a comprehensive assessment at enrollment and periodically thereafter to evaluate their functional status, co-morbid conditions, and overall well-being. The study also seeks to gather data on patient care patterns and satisfaction, while banking blood samples for future research on genetic markers related to aging. This longitudinal approach will help inform future studies and improve understanding of PCDs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients have an outpatient appointment or are hospitalized inpatient at UNC Cancer Hospitals, or affiliated clinic settings or participating sites for the evaluation and management of a PCD.
* Patients have a documented diagnosis of PCD defined as the presence of a monoclonal protein and/or monoclonal plasma cell population. Examples of PCDs include but are not limited to monoclonal gammopathy of uncertain significance; smoldering myeloma; multiple (active) myeloma; plasma cell leukemia; Castleman's disease; amyloidosis; light and/or heavy chain deposition disease; Polyneuropathy, Organomegaly, Endocrinopathy,Monoclonal gammopathy and Skin changes (POEMS) syndrome; and cryoglobulinemia.
* Age ≥18 years.
* Must consent to participation in this study and agree to complete the assessment at baseline and follow-up time points.
* Must be able to read and speak English.

Exclusion Criteria:

* Physical or psychiatric/behavioral illnesses or problems that the treating clinician feels would preclude successful participation in the study.
* There are no imaging or lab studies required to determine eligibility.

Where it's running

• North Carolina Cancer Hospital
  Chapel Hill, North Carolina, United States Recruiting

Study contacts

• Principal investigator: Sascha Tuchman, MD — UNC Lineberger Comprehensive Cancer Center
• Study coordinator: Nicholas Mangieri
• Email: nicholas_mangieri@med.unc.edu
• Phone: (919) 966-4432

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Prolonged overnight fasting combined with a Mediterranean-style diet for people with multiple myeloma or precursor conditions

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• In-home cancer treatment with remote specialist support for patients in the Florida Panhandle

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• Using Whole Body MRI to Improve Cancer Detection

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  Recruiting at 2 sites Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS · Bologna, BO and 2 other locations · NCT06895291

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.