Reducing tobacco use in people living with HIV in Switzerland

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial aims to evaluate the effectiveness of various tobacco smoking substitution products, including e-cigarettes and nicotine pouches, in helping smokers living with HIV achieve a 7-day tobacco cigarette abstinence at 6 months. Participants will be recruited from the Swiss HIV Cohort Study and will receive these alternatives alongside usual care. The study addresses the high prevalence of smoking among people living with HIV, focusing on harm reduction strategies to improve health outcomes. By comparing these newer products to traditional nicotine replacement therapies, the trial seeks to identify more effective cessation methods.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Signed informed consent for the data collection and participation in the SHCS (Cohort consent).
* Signed informed consent to be randomized to future interventions (Randomization consent).
* Age 18 years or older.
* Smoked one or more tobacco cigarettes per day (smoking status = yes) at the time of enrolment.

Exclusion Criteria:

* Currently using e-cigarettes or nicotine pouches or nicotine patches.
* Pregnant women.

Where it's running

• Inselspital Bern
  Bern, Canton of Bern, Switzerland Recruiting
• Cantonal Hospital St. Gallen
  Sankt Gallen, Canton of St. Gallen, Switzerland Recruiting
• University Hospital Lausanne
  Lausanne, Canton of Vaud, Switzerland Recruiting
• University Hospital Zurich
  Zurich, Canton of Zurich, Switzerland Recruiting
• Cantonal Hospital Aarau
  Aarau, Switzerland Recruiting
• University Hospital Geneva
  Geneva, Switzerland Recruiting

Study contacts

• Principal investigator: Matthias Briel, Prof. — University Hospital, Basel, Switzerland
• Study coordinator: Matthias Briel, Prof.
• Email: matthias.briel@usb.ch
• Phone: + 4161 265 3815

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.