Reducing postoperative pain and nausea after hysteroscopy with lidocaine infusion

A New Alternative for Postoperative Pain Control Following Hysteroscopy;Preoperative Intravenous Lidocaine

Not applicable Interventional Afyonkarahisar Health Sciences University · NCT06423456

This study tests if giving lidocaine during hysteroscopy can help women feel less pain and nausea after the procedure compared to those who get a saline solution.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment160 (estimated)
Ages19 Years to 65 Years
SexFemale
SponsorAfyonkarahisar Health Sciences University Academic / other
Locations1 site (Merkez, Afyonkarahi̇sar)
Trial IDNCT06423456 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of intraoperative lidocaine infusion on postoperative pain and nausea in patients undergoing hysteroscopy. A total of 150 female patients scheduled for elective hysteroscopy will be divided into two groups: one receiving lidocaine and the other receiving saline as a control. The aim is to determine if lidocaine can reduce the need for opioids and improve recovery outcomes. The study focuses on common gynecological conditions treated with hysteroscopy, such as abnormal uterine bleeding and endometrial pathologies.

Who should consider this trial

Good fit: Ideal candidates are female patients aged 18 and older with ASA I-II classification scheduled for elective hysteroscopy due to conditions like abnormal uterine bleeding or infertility.

Not a fit: Patients under 18, those allergic to lidocaine, or with chronic pain or severe systemic diseases may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve postoperative recovery by reducing pain and nausea for patients undergoing hysteroscopy.

How similar studies have performed: Previous studies have shown that intraoperative lidocaine can effectively reduce postoperative pain and opioid use, suggesting a promising approach in this context.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Female patients with ASA I-II according to the American Society of Anesthesiologists (ASA) classification who are scheduled for elective hysteroscopy with indications such as
* abnormal uterine bleeding
* endometrial polyp
* submucosal myoma
* foreign body in the endometrial cavity
* infertility
* intrauterine synechia

Exclusion Criteria:

* Patients under the age of 18
* Who are allergic to lidocaine addicted to opioids or NSAIDs
* Patients with chronic pain
* Patients with severe systemic disease
* Patients who do not approve

Where this trial is running

Merkez, Afyonkarahi̇sar

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postoperative PainPostoperative NauseaAnalgesiahysteroscopyintraoperative lidocainepostoperative painpostoperative nausea
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.