RaDIANT health system changes to speed transplant evaluation
Official title: The RaDIANT Health Systems Intervention for Improving Access to Kidney Transplantation
Run by Indiana University · NCT07033117 · Data updated 2026-11-12
This study tests whether system-level changes in transplant care can help more people move through evaluation sooner after dialysis referral.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 14000 (estimated) |
| Sponsor | Indiana University Academic / other |
| Locations | 5 sites (Atlanta, Georgia and 4 other locations) |
| Status | Recruiting |
| Started | October 27, 2025 |
| Main results expected | March 31, 2027 |
| Study ends | July 31, 2027 |
| Registry record updated | May 26, 2026 |
| Trial ID | NCT07033117 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults with ESRD enrolled at participating dialysis centers who are referred to one of the five partner transplant centers and are at the start of the evaluation process.
✕Probably not a fit
Patients referred to non-participating centers or not advancing in the evaluation process at these centers may not experience benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study examines whether providing performance feedback, increasing dialysis facility awareness, and proactive patient and provider outreach can reduce delays in referral and completion of transplant evaluation for patients with ESRD. It involves five large transplant centers and about 800 referring dialysis centers, and uses targeted interventions at the health-system level to address upstream barriers. Primary actions include feedback reports on referral/evaluation closures, a dialysis facility awareness campaign, patient contact via preferred method, and direct phone outreach to dialysis facilities and providers during the patient’s dialysis session. The trial is led by Indiana University with collaboration from NIDDK and affiliated health systems across Atlanta, Duke, Medical University of South Carolina, and Indiana.
Why it matters
Potential benefit: If successful, the approach could shorten time to transplant evaluation and improve access to transplantation for patients receiving dialysis.
How similar studies have gone: Previous work in system-level interventions has shown promise in improving care pathways, but this exact combination of upstream, facility-focused strategies for transplant evaluation is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Five large transplant centers (Emory Transplant Center and Piedmont Transplant Center in Atlanta, GA; Medical University of SC; Duke University in Durham, NC; and Indiana University in Indianapolis, IN) \~800 referring dialysis center referring to these transplant centers Exclusion Criteria: * Individuals referred, initiating evaluation, and waitlisted at non-participating start centers
Where it's running
-
Piedmont Transplant Institute
Atlanta, Georgia, United States Recruiting -
Emory Transplant Center
Atlanta, Georgia, United States Recruiting -
IU Health Transplant - Indianapolis
Indianapolis, Indiana, United States Recruiting -
Duke Transplant Center
Durham, North Carolina, United States Recruiting -
MUSC Mid-Carolinas Transplant Center
Lancaster, South Carolina, United States Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.