Quality of life after total prostatectomy vs focal HIFU for favorable intermediate-risk localized prostate cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Men with localized, favorable intermediate-risk prostate cancer are assigned to one of two treatments—total prostatectomy or focal HIFU—to compare their cancer-related quality of life. Participants complete the EPIC-CP questionnaire at 6, 12, and 24 months after treatment to measure outcomes. The study aims to identify differences in urinary, bowel, sexual, and hormonal functions between the two approaches. It is conducted at Clinique La Croix du Sud in Quint-Fonsegrives under the lead sponsor GCS Ramsay Santé pour l'Enseignement et la Recherche.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient, male, aged between ≥ 40 and ≤ 75 years
* Patient with a life expectancy \> 10 years at the time of inclusion.
* Patient with a therapeutic strategy (prostatectomy or focal HIFU) defined during a PCR.
* Patient with a diagnosis of localised prostate cancer at favourable intermediate risk
* Patient able to tolerate general anaesthesia or type IV sedation
* Patient with normal urinary continence status
* Patient with satisfactory erectile function allowing penetration:
* Patient with targeted biopsies and systematic biopsies
* Patient affiliated to or benefiting from a social security scheme
* French-speaking patients who do not object to the use of their data.

Exclusion Criteria:

* Patients with a contraindication to MRI
* Stage T3a or b on MRI
* Patient on long-term anticoagulants and unable to stop them.
* Patient already included in another study
* Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision

Where it's running

• Clinique La Croix du Sud
  Quint-Fonsegrives, France Recruiting

Study contacts

• Study coordinator: Guillaume PLOUSSARD, MD
• Email: dr.gploussard@gmail.com
• Phone: +33 06 84 11 85 09

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.