Quadro-Iliac Plane Block to Ease Pain After Lumbar Microdiscectomy
Official title: Effect of Ultrasound-Guided Quadro-Iliac Plane Block Compared With Local Infiltration Analgesia After Single-Level Lumbar Microdiscectomy: A Prospective, Double-Blind, Controlled, Multicenter Randomized Trial
Run by Kanuni Sultan Suleyman Training and Research Hospital · NCT07695987 · Data updated 2026-11-12
This trial tests whether a bilateral ultrasound-guided quadro-iliac plane block, added to standard pain medicine, reduces the amount of fentanyl needed in the first 24 hours after single-level lumbar microdiscectomy compared with local infiltration analgesia.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Kanuni Sultan Suleyman Training and Research Hospital Academic / other |
| Locations | 1 site (Istanbul, Istanbul) |
| Status | Recruiting |
| Started | July 10, 2026 |
| Main results expected | December 1, 2026 |
| Study ends | December 2, 2026 |
| Registry record updated | July 30, 2026 |
| Trial ID | NCT07695987 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18–75 years old, ASA I–III, scheduled for elective single-level lumbar microdiscectomy under general anesthesia.
✕Probably not a fit
Patients who do not experience improved pain control with regional blocks or who have contraindications to nerve blocks may not see benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults undergoing elective single-level lumbar microdiscectomy are randomized to receive either a bilateral quadro-iliac plane block with postoperative patient-controlled analgesia or local infiltration analgesia with the same analgesia approach. The main endpoint is total fentanyl use in the first 24 hours after surgery, with secondary endpoints including pain scores, need for additional analgesia, opioid-related side effects, dermatomal spread of anesthesia, and recovery quality. The study is prospective, randomized, double-blind where possible, and multicenter, comparing two analgesia strategies under a standardized anesthesia protocol. Outcomes will inform whether the plane block provides superior postoperative pain control and opioid-sparing benefits.
Why it matters
Potential benefit: If successful, patients may experience better pain relief and less opioid use after surgery.
How similar studies have gone: Previous work in regional anesthesia for spine surgery has shown benefits with certain blocks, but this specific quadro-iliac plane block approach for this procedure is novel/under investigation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 to 75 years * American Society of Anesthesiologists physical status I to III * Scheduled for elective single-level lumbar microdiscectomy, such as L4-L5 or L5-S1 disc herniation * Planned surgery under general anesthesia * Able to provide written informed consent Exclusion Criteria: * Allergy or hypersensitivity to local anesthetics * Coagulopathy or active anticoagulant use * Infection, scar tissue, or skin lesion at the injection site * Pregnancy or breastfeeding * Chronic pain syndrome or regular opioid use * American Society of Anesthesiologists physical status IV or higher * Planned surgery for two or more levels of disc herniation
Where it's running
-
Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital
Istanbul, Istanbul, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Engin ihsan Turan, principal investigator
- Email: drenginihsan@gmail.com
- Phone: +905382431114
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.