QUAD-HF registry for people with new heart failure and LVEF under 50%

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

QUAD-HF is a prospective observational registry enrolling adults in the United Kingdom who receive a new diagnosis of heart failure with left ventricular ejection fraction (LVEF) <50% within 12 weeks. The registry will collect real-world data on diagnoses, treatments, guideline implementation, and service access across participating centers. Participants will be followed longitudinally for clinical outcomes such as hospitalizations and mortality. The goal is to characterize care variation and links between treatment use and outcomes in an unselected patient population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age \>18 years
2. Newly diagnosed Heart Failure with a Left Ventricular Ejection Fraction \<50% (≤12 Weeks prior to enrolment).
3. Able and willing to consent.

Exclusion Criteria:

1. LVEF 50% or more at time of diagnosis
2. Palliative care
3. Unable or unwilling to give consent

Where it's running

• Mid and South Essex NHS Foundation Trust
  Basildon, Essex, United Kingdom Recruiting
• British Heart Foundation Glasgow Cardiovascular Research Centre, Glasgow
  Glasgow, United Kingdom Not yet recruiting

Study contacts

• Principal investigator: Henry Oluwasefunmi Savage — Mid and South Essex NHS Foundation Trust
• Study coordinator: Henry Oluwasefunmi Savage, MD FRCP
• Email: henry.savage@nhs.net
• Phone: +44 01268524900

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.