Clinical trial Recruiting at 1 site Observational Ages 17 and up

Pulmonary arterial hypertension patient registry — Hospital Italiano de Buenos Aires

Official title: Pulmonary Hypertension Institutional Registry at Hospital Italiano de Buenos Aires

Run by Hospital Italiano de Buenos Aires · NCT01501838 · Data updated 2026-11-12

This registry collects medical and heart‑lung test information from adults with pulmonary arterial hypertension treated at Hospital Italiano de Buenos Aires to follow their health and treatments over time.

More Pulmonary Arterial Hypertension trials

Quick facts

Study typeObservational
Ages17 Years and up
SexAll
Enrollment200 (estimated)
SponsorHospital Italiano de Buenos Aires
Academic / other
Locations1 site (Buenos Aires, Buenos Aires)
StatusRecruiting
StartedJanuary 1, 2017
Main results expectedDecember 31, 2030
Study endsJune 1, 2031
Registry record updatedAugust 24, 2025
Trial IDNCT01501838 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (≥18 years) with WHO Group 1 pulmonary arterial hypertension who are entered in the Hospital Italiano de Buenos Aires institutional registry and meet the center's hemodynamic criteria.

Probably not a fit

Patients who had a lung transplant before baseline or who are not treated at Hospital Italiano de Buenos Aires (or do not meet the hemodynamic criteria) are unlikely to benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Institutional Registry at Hospital Italiano de Buenos Aires enrolls adults with WHO Group 1 pulmonary arterial hypertension using 2022 ESC/ERS hemodynamic criteria. It combines prospectively enrolled incident cases with prevalent HMO patients who were diagnosed before the registry began. Clinical, hemodynamic, treatment, and outcome data are recorded to characterize disease course and real‑world management. As an observational single‑center registry, it does not assign interventions but documents routine clinical care.

Why it matters

Potential benefit: If successful, the registry could improve understanding of local disease patterns and treatment outcomes to help guide better care for patients with PAH.

How similar studies have gone: Other national and international PAH registries have successfully provided important epidemiologic and outcome data, so this approach is well established.

Who can join: the full rules

Show full inclusion / exclusion criteria
* Inclusion Criteria:

  1. Diagnosed with PAH WHO group 1 (2022 ESC/ESR guidelines criteria) as the presence of a mean pulmonary artery pressure (mPAP) greater than 20 mmHg at rest with pulmonary arterial wedge pressure (PAWP) \>15 mmHg and pulmonary vascular resistance (PVR) \>2 WU, according to the 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension.
  2. Included in the institutional registry of PAH of Hospital Italiano de Buenos Aires
  3. Aged ≥18 years at the index date.
* Exclusion Criteria History of lung transplantation surgery previously the baseline period

Where it's running

  • Hospital Italiano de Buenos Aires
    Buenos Aires, Buenos Aires, Argentina
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • PADN treatment for pulmonary arterial hypertension

    This project will try pulmonary artery denervation (PADN) with the Enhancor radiofrequency catheter in people with pulmonary arterial hypertension who underwent the procedure since March 2024 to collect real-world outcomes.

    Recruiting Pulnovo Medical (Wuxi) Co., Ltd. · Nanjing, Jiangsu · NCT07039604

  • Understanding how low-load leg exercises affect muscle and blood flow in PAH patients

    This substudy tests whether a gentle leg exercise program can change blood flow and oxygen use in the calf muscles of adults with pulmonary arterial hypertension.

    Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT07781709

  • Sotatercept in Japanese children with pulmonary arterial hypertension

    This study tests whether sotatercept is safe and well tolerated in Japanese children with PAH when added to standard PAH treatment.

    Recruiting at 3 sites Phase 2 Merck Sharp & Dohme LLC · Izumi, Osaka and 2 other locations · NCT07646860

  • DIAG723 in Adults With HHT

    A first-in-human study tests DIAG723 versus placebo in adults with hereditary hemorrhagic telangiectasia to see if it is safe and possibly helpful.

    Recruiting at 3 sites Phase 1/2 Diagonal Therapeutics, Inc. · Camperdown, New South Wales and 10 other locations · NCT07623525

  • See if 18F-FAPI-74 PET/CT can better detect fibrosis in heart and lung disease

    Researchers are testing a new PET/CT tracer, 18F-FAPI-74, to see if it can reveal early fibrotic changes in people with heart and lung diseases who are at risk for tissue scarring.

    Recruiting Phase 3 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07613099

  • Sotatercept in Indian adults with pulmonary arterial hypertension on standard therapy

    This study tests whether adding sotatercept to current PAH medicines is safe and tolerable for adults with PAH in India.

    Recruiting at 3 sites Phase 4 Merck Sharp & Dohme LLC · Hyderabad, Andhra Pradesh and 2 other locations · NCT07600723

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.