Psychotherapy program for postpartum depression

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial evaluates a novel psychotherapy called Engage & Connect, designed to reduce postpartum depression by enhancing social engagement and support. Over a 9-week period, participants will receive either the Engage & Connect intervention or a Symptom Review and Psychoeducation intervention, both delivered remotely. The study aims to assess changes in social isolation, social reward processing, and depression severity among mothers experiencing postpartum depression.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Up to 1 year post-delivery
2. Edinburgh Postnatal Depression Scale (EPDS) score ≥ 10.
3. Off antidepressants or on a stable dose of an antidepressant for 8 weeks and do not intend to change the dose in the next 10 weeks.
4. Capacity to provide consent for research assessment and treatment.
5. Speaks English proficiently

Exclusion Criteria:

1. Intent or plan to attempt suicide in the near future
2. Ongoing psychotherapy (no more than once every 8 weeks or during the duration of the intervention)
3. Active substance abuse or dependence
4. Severe fetal anomalies, stillbirth or infant death at time of enrollment for index pregnancy
5. History or presence of psychiatric diagnoses other than major depressive disorder without psychotic features, generalized anxiety disorder, persistent depressive disorder, or specific phobia.
6. Use of psychotropic drugs or cholinesterase inhibitors other than use of ≤ 0.5 mg of lorazepam daily up to seven times per week.

Where it's running

• Weill Cornell Medicine
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Nili Solomonov, PhD — Weill Medical College of Cornell University
• Study coordinator: Nili Solomonov, PhD
• Email: nis2051@med.cornell.edu
• Phone: 212-746-5886

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Postpartum Depression: A Digital Decision Support Tool for Providers

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• Empowering mothers to prevent postpartum depression

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.