Psychological well-being, depression, and quality of life in adults with type 2 diabetes
Official title: A Cross-Sectional Observational Study to Evaluate Psychological Well-Being, Depression, and Health-Related Quality of Life and Their Demographic and Clinical Correlates in Adults With Type 2 Diabetes Attending an Outpatient Metabolic Clinic
Run by National Taiwan University Hospital · NCT07241325 · Data updated 2026-11-12
This project will see if psychological well-being and depressive symptoms are linked to health-related quality of life in adults with type 2 diabetes attending an outpatient clinic.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | September 19, 2025 |
| Main results expected | June 30, 2026 |
| Study ends | October 1, 2026 |
| Registry record updated | January 28, 2026 |
| Trial ID | NCT07241325 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older with diagnosed type 2 diabetes who receive outpatient care at NTUH, can read and complete Chinese questionnaires, and can provide written informed consent.
✕Probably not a fit
People with major psychiatric disorders, moderate to severe cognitive impairment, acute diabetic complications, hospitalization, or severe communication barriers are excluded and unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective cross-sectional observational project will enroll about 350 adults with type 2 diabetes from the outpatient metabolic clinic at National Taiwan University Hospital. Participants who can read Chinese will complete the EQ-5D-5L, PHQ-9, and the Shalom Scale along with demographic and clinical measures such as BMI, HbA1c, disease duration, and psychosocial support indicators. The analysis will use descriptive statistics, Pearson correlations, ANOVA, and multiple linear regression to identify factors associated with psychological well-being. Findings are intended to inform tailored mental health and quality-of-life interventions for this patient population.
Why it matters
Potential benefit: If successful, the results could help tailor mental health and support services to improve quality of life for people with type 2 diabetes.
How similar studies have gone: Previous observational studies have found links between depressive symptoms, psychological well-being, and quality of life in type 2 diabetes, so this study builds on established findings in a Taiwanese clinic population.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Adults aged 18 years or older with full legal capacity. 2. Clinically diagnosed with Type 2 Diabetes Mellitus and receiving ongoing outpatient care. 3. Able to read and understand Chinese questionnaires and complete self-administered forms. 4. Understand the study purpose and procedures and provide written informed consent. Exclusion Criteria: 1. Presence of major psychiatric disorders (e.g., schizophrenia, bipolar disorder, major depressive disorder). 2. Moderate to severe cognitive impairment or dementia, as assessed by the clinical physician, making it impossible to complete the questionnaires. 3. Currently experiencing acute diabetic complications (e.g., diabetic ketoacidosis, hyperosmolar hyperglycemic state) or hospitalization. 4. Severe language or other communication barriers preventing expression of consent or understanding of study content.
Where it's running
-
National Taiwan University Hospital - Metabolism
Taipei, Taiwan Recruiting
Study contacts
- Principal investigator: Ching-Yuan Wang — National Taiwan University Hospital, Department of Internal Medicine (Metabolism)
- Study coordinator: Yi-Chieh Chung, Msn, Rn
- Email: ejchung@gmail.com
- Phone: +886-2-2312-3456
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Predicting depression in patients after heart surgery
This study is trying to see if a new tool can help predict which patients might develop depression after heart surgery, so they can get help sooner.
-
Lifestyle change program to help type 2 diabetes go into remission in Pakistan
This study tests whether a structured, plant-predominant lifestyle program can put adults with type 2 diabetes in Lahore, Pakistan into remission for the first six months.
-
Intraoperative Comfort After Cesarean with Neuraxial Anesthesia
This study tests how patients feel during cesarean delivery with spinal or epidural anesthesia to help create a tool that captures intraoperative comfort.
-
Colchicine for preventing cardiovascular disease in adults with type 2 diabetes
A 24-week study will test whether low-dose colchicine can help protect blood vessels in adults with type 2 diabetes who have not yet developed artery disease, compared with a placebo.
-
MWN105 injection in overweight or obese adults you may join
This early-phase trial tests whether MWN105 is safe and tolerable in overweight or obese adults in China, using a placebo comparison.
-
MWN109 tablets in adults with type 2 diabetes mellitus
A phase 2 trial tests MWN109 tablets versus placebo (and against active control semaglutide) to see if the medicine helps adults with type 2 diabetes lower their blood sugar.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.