Psychological interventions for breast cancer survivors

The Effectiveness of Mobile-based Psychological Interventions in Reducing Psychological Distress and Preventing Stress-related Changes in Psycho-neuroendocrine-immune Network in Breast Cancer Survivors- Randomized Controlled Trial

Not applicable Interventional Masaryk University · NCT05406531

This study is testing whether three different online mental health programs can help breast cancer survivors feel better and improve their stress levels.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment440 (estimated)
Ages18 Years and up
SexFemale
SponsorMasaryk University Academic / other
Locations1 site (Brno, Bohunice)
Trial IDNCT05406531 on ClinicalTrials.gov

What this trial studies

This study examines the effectiveness of three different psychological interventions delivered through a mobile application on the psycho-neuroendocrine-immune system in breast cancer survivors. Researchers will measure the impact of these interventions on various stress-related biomarkers, including cortisol and heart rate variability, as well as psychological variables. The study aims to provide clearer outcomes by recruiting a homogeneous sample of patients and conducting follow-up measurements at 3 and 9 months. The interventions include Mindfulness-Based Cognitive Therapy, Positive Psychology, and Autogenic Training, all provided online.

Who should consider this trial

Good fit: Ideal candidates for this study are women over the age of 18 who have completed adjuvant treatment for breast cancer.

Not a fit: Patients with severe psychiatric disorders or those lacking access to mobile devices or the internet may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the psychological and immune health of breast cancer survivors, potentially improving their overall well-being.

How similar studies have performed: Previous studies have shown promising results for psychological interventions in cancer care, but this specific approach using mobile applications is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women over the age of 18
* Breast cancer patients at the end of adjuvant treatment

Exclusion Criteria:

* Patients without a mobil device ("smart" mobile phone)
* Patients without internet access
* Patients with diagnosed: psychotic disorder; severe depressive episode; panic disorder; bipolar disorder; personality disorder associated with uncontrollable mood swings; PTSD; suicidal attempts and active suicidal ideation; disability pension due to non-specific mental or somatic problems; hospitalization due to a psychiatric disorder in the past year

Where this trial is running

Brno, Bohunice

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Breast Cancer FemaleBreast Cancer Stage IBreast Cancer Stage IIBreast Cancer Stage IIIBiomarkersmHealthpsychological intervention
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.