Protein after exercise to improve body composition in breast cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study examines the effect of post-workout whey protein supplementation (60 grams) in addition to a resistance-training program for women who have completed breast cancer treatment. Participants will engage in structured resistance training and will receive either the protein supplement or no protein to compare changes in body composition, including muscle mass and percentage body fat. The trial targets adults 20–89 with a biopsy-confirmed breast cancer history and excludes those currently receiving cytotoxic chemotherapy. Immunotherapy or targeted therapies are allowed. Outcomes focus on whether the protein supplement enhances gains from exercise beyond exercise alone. The study is led by Allegheny Singer Research Institute at AHN Allegheny General Hospital with locations in Pittsburgh, PA.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 20-89 years
2. Women prescribed exercise as a SOC
3. Women with a biopsy proven diagnosis of ductal carcinoma in situ (DCIS) or invasive carcinoma of the breast
4. Women must have undergone treatment for breast cancer, including one or more of the following: surgery, radiation therapy, chemotherapy, immunotherapy, or hormonal therapy. Women undergoing active chemotherapy are not allowed on study. Immunotherapy or targeted agent usage is allowed.
5. Women with \> 3 months of resistance training experience under expert guidance by a CSCS
6. Must be able to read and understand English and consent for themselves.

Exclusion Criteria:

1. Any current treatment with cytotoxic chemotherapy for breast cancer
2. Inability to safely engage in group sessions of resistance training as deemed by study PI
3. Severe arthritic, joint, cardiovascular, or musculoskeletal condition deemed by PI to be unsafe to engage in resistance training
4. Beta blocker or GLP-1 inhibitor medications
5. Pregnant women
6. Males
7. Lactose intolerance
8. Cow's milk or whey protein allergy

Where it's running

• AHN Allegheny General Hospital
  Pittsburgh, Pennsylvania, United States Recruiting
• AHN Allegheny General Hospital
  Pittsburgh, Pennsylvania, United States Not yet recruiting

Study contacts

• Principal investigator: Colin Champ, MD, CSCS — AHN Radiation Oncology
• Study coordinator: Clinical Trials Contact
• Email: ctgov@ahn.org
• Phone: 412-330-6151

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.