Prone versus supine positioning for infants with acute breathing problems

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an open-label, randomized crossover study enrolling 40 infants under 12 months hospitalized with infection-triggered acute respiratory insufficiency who require CPAP or high-flow oxygen. Each child will spend one hour in the prone position and one hour in the supine position while receiving respiratory support, with the order randomized. Respiratory rate and a symptom score will be recorded to compare respiratory function between positions. The trial is conducted at Hans Christian Andersen's Children's Hospital, Odense University Hospital.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 0-12 months
* Clinical respiratory infection
* Physician-ordered High-Flow oxygen or CPAP
* Consent from the legal guardian

Exclusion Criteria:

* Significant chronic pulmonary, cardiac, or neurological disorders
* Children admitted to intensive care

Where it's running

• Hans Christian Andersen´s Childrens Hospital
  Odense, Denmark Recruiting

Study contacts

• Study coordinator: Josefine Gradman, MD, PhD
• Email: josefine.gradman@rsyd.dk
• Phone: +4529241375

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.