Program to eliminate mother-to-child transmission of HIV, syphilis, and HBV
Integrated Antenatal Screening for HIV, Syphilis, and Hepatitis B Virus (HBV) in Pregnant Women in Burkina Faso and The Gambia
This study is testing a new program in Burkina Faso and The Gambia to see if better training for healthcare workers and quick tests can help stop the spread of HIV, syphilis, and hepatitis B from mothers to their babies.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 2800 (estimated) |
| Sex | Female |
| Sponsor | Institut de Recherche pour le Developpement Government |
| Locations | 2 sites (Bobo-Dioulasso and 1 other locations) |
| Trial ID | NCT05951751 on ClinicalTrials.gov |
What this trial studies
The TRI-MOM program aims to implement and evaluate a simplified and integrated strategy for the triple elimination of mother-to-child transmission (MTCT) of HIV, syphilis, and HBV in Burkina Faso and The Gambia. This program consists of a pilot study that reinforces antenatal screening and prevention capacities through training healthcare professionals and utilizing rapid diagnostic tests. Additionally, it includes an evaluation component to assess the impact of the TRI-MOM strategy on PMTCT services and women's empowerment. The program will be conducted in nine selected maternal and child health facilities.
Who should consider this trial
Good fit: Ideal candidates for this program are women attending postnatal visits at selected maternity facilities.
Not a fit: Patients who refuse to participate or are unable to provide consent will not benefit from this program.
Why it matters
Potential benefit: If successful, this program could significantly reduce the rates of mother-to-child transmission of HIV, syphilis, and HBV, improving maternal and child health outcomes.
How similar studies have performed: Other studies have shown success with integrated approaches to eliminate mother-to-child transmission of infectious diseases, indicating that this strategy has potential.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women attending a postnatal visit in one of the selected maternities (no maternal age limit) Exclusion Criteria: * Refusal to participate in the study * Unable to provide consent
Where this trial is running
Bobo-Dioulasso and 1 other locations
- Centre Muraz/INSP — Bobo-Dioulasso, Burkina Faso (Not_yet_recruiting)
- MRC The Gambia at LSHTM — Fajara, The Gambia (Recruiting)
Study contacts
- Principal investigator: Sylvie Boyer, PhD — Umr 1252 Sesstim
- Study coordinator: Lauren Perieres, PhD
- Email: lauren.perieres@inserm.fr
- Phone: +33 4.91.32.46.00
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.