Program for managing knee osteoarthritis in primary care

Risk Assessment and Management Program (RAMP) on Knee Osteoarthritis in Primary Care- a One-year Pragmatic Randomized Controlled Trial

Not applicable Interventional Chinese University of Hong Kong · NCT06283147

This study is testing a new support program for adults with knee osteoarthritis to see if it helps reduce pain and improve their daily activities compared to regular care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment228 (estimated)
Ages45 Years and up
SexAll
SponsorChinese University of Hong Kong Academic / other
Locations1 site (Hong Kong)
Trial IDNCT06283147 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of a Chronic Care Model called the Risk Assessment and Management Program on Knee Osteoarthritis (RAMP-Knee OA) in adults suffering from knee osteoarthritis. Participants will be randomly assigned to either the RAMP-Knee OA group, which includes structured support and consultations, or a usual care group. The study will assess various outcomes, including pain relief and improvements in physical function and quality of life, over a 52-week period. Participants will undergo assessments at baseline, and at 16, 32, and 52 weeks to measure the program's impact.

Who should consider this trial

Good fit: Ideal candidates are adults diagnosed with moderate to severe knee osteoarthritis and experiencing significant pain.

Not a fit: Patients with serious knee pathologies, previous knee replacements, or those unable to participate reliably may not benefit from this program.

Why it matters

Potential benefit: If successful, this program could significantly improve pain management and quality of life for patients with knee osteoarthritis.

How similar studies have performed: Previous studies utilizing Chronic Care Models have shown promise in managing chronic conditions, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosis of Knee OA based on clinical criteria of the American Rheumatology College
* Moderate to severe Knee pain for 3 months or longer (average score of 4 or greater on a 0-10 pain scale in the past 3 months)

Exclusion Criteria:

* Participants with potential serious knee pathology (e.g. inflammatory arthritis, acute trauma, malignancy)
* Previous Knee replacement
* Scheduled knee joint replacement surgery within 1 year
* Participants who are unable to reliably participate (e.g. those who do not speak Chinese or unable to attend study intervention)

Where this trial is running

Hong Kong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Knee OsteoarthritisRisk assessment and Management ProgrammeChronic Care Model
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.