Preventing nausea and vomiting after surgery using electrical stimulation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of percutaneous electrical nerve stimulation at the Pericardium 6 (PC6) point using a wearable device to prevent postoperative nausea and vomiting in patients undergoing elective laparoscopic surgery. Approximately 302 participants will be randomly assigned to receive either active electrical stimulation or a placebo wristband. The stimulation will occur 30 minutes before surgery and continue for 24 hours postoperatively. The primary outcome is the incidence of postoperative nausea and vomiting, with secondary outcomes including recovery metrics and complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients aged 18-65 years;
2. Patients undergoing elective laparoscopic surgery;
3. American Society of Anaesthesiologists(ASA) Grade 1 to 3;
4. Anesthesia: General Anesthesia, Tracheal Intubation;
5. BMI: ≥18, \<28;
6. Gender: female
7. Patients or their family members are able to comprehend the study protocol and are willing to participate in this research by providing written informed consent.

Exclusion Criteria:

1. There are incisions or scars in the wearing position of the device;
2. There is a local infection in the wearing position of the device;
3. upper extremity nerve injury;
4. history of spinal cord surgery;
5. Participated in other clinical trials within 4 weeks;
6. suffering from severe central nervous system disease or mental disorder;
7. Patients need to return to the ICU after surgery.

Where it's running

• Peking Union Medical College Hospital
  Beijing, China Recruiting

Study contacts

• Study coordinator: Chen Junjie
• Email: 1045034956@qq.com
• Phone: +8617330860407

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• See how nasal ondansetron compares to IV in healthy adults

  This study tests whether a nasal spray form of ondansetron delivers similar blood levels as the IV version in healthy adults.

  Recruiting Phase 1 Nasus Pharma · Jerusalem · NCT07868861

• Postoperative nausea, vomiting and pain after bariatric surgery in Sweden

  This study looks at how often people have nausea, vomiting, and pain after bariatric surgery in Sweden and whether anesthesia type or regional blocks affect those outcomes.

  Recruiting at 2 sites Umeå University · Sundsvall and 1 other locations · NCT07797374

• Time to first rescue antiemetic after two dual-drug regimens for PONV in gallbladder surgery

  This trial tests whether ondansetron plus metoclopramide delays the need for rescue antiemetic more than dexamethasone plus metoclopramide in adults at moderate-to-high risk undergoing laparoscopic cholecystectomy.

  Recruiting Phase 4 Faisalabad Medical University · Faisalābad, Punjab Province · NCT07638527

• Comfort Tote to help recovery after scoliosis surgery in teens

  This study tests whether a therapeutic Comfort Tote can reduce pain and anxiety after surgery for adolescent idiopathic scoliosis.

  Recruiting Columbia University · New York, New York · NCT07632833

• Menstrual cycle effects on optic nerve sheath diameter during laparoscopic gynecologic surgery

  This study will try to see if menstrual cycle phase changes the optic nerve sheath size and affects postoperative nausea, vomiting, and thinking in women having elective laparoscopic gynecologic surgery.

  Recruiting Konya City Hospital · Konya · NCT07539831

• High- vs low-dose propofol to reduce nausea after coronary bypass

  We will see if giving higher-dose propofol during coronary artery bypass surgery reduces postoperative nausea and vomiting in adults having elective CABG.

  Recruiting Istanbul University - Cerrahpasa · Istanbul, Outside of the US · NCT07386379

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.