Menstrual cycle effects on optic nerve sheath diameter during laparoscopic gynecologic surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this single-site observational study at Konya City Hospital, women aged 18–45 scheduled for elective laparoscopic gynecologic surgery will be grouped by menstrual phase (follicular versus luteal). Perioperative optic nerve sheath diameter (ONSD) measurements will be taken and postoperative nausea and vomiting plus cognitive function (using the Mini-Mental State Examination and verbal descriptive scales) will be recorded. Key exclusions include irregular menstrual cycles, pregnancy or breastfeeding, neurological or eye diseases affecting intracranial pressure, prior brain surgery, and uncontrolled severe cardiovascular disease. The study aims to see whether normal hormonal fluctuations across the menstrual cycle are associated with differences in ONSD and short-term postoperative outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female patients aged 18 to 45 years
* Scheduled for elective laparoscopic gynecologic surgery
* Menstrual cycle in the follicular phase or luteal phase
* American Society of Anesthesiologists (ASA) physical status I-II

Exclusion Criteria:

* Irregular menstrual cycle (e.g., polycystic ovary syndrome, early menopause, hypothalamic amenorrhea)
* Pregnancy or breastfeeding
* Neurological disease associated with intracranial pressure changes
* Glaucoma or another eye disease associated with high intraocular pressure
* Previous brain surgery
* Uncontrolled hypertension or severe cardiovascular disease

Where it's running

• Konya City Hospital
  Konya, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Mahmut Tutar, Md — Konya City Hospital
• Study coordinator: Mahmut Tutar, Md
• Email: masatu42@gmail.com
• Phone: 905552723704

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.